Separation of citric acid from gluconic acid in fermentation...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

Reexamination Certificate

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C562S580000

Reexamination Certificate

active

07439392

ABSTRACT:
Citric acid is separated from a fermentation broth containing gluconic acid by using an adsorbent comprising a water-insoluble, macroreticular or gel, strongly or weakly basic anionic exchange resin possessing quaternary or tertiary amine functional groups, said a anionic exchange resin having a cross-linked acrylic or styrene resin matrix and a desorbent comprising water or dilute sulfuric acid. The pH of the feed is maintained below the first ionization constant (pKa1) of citric acid to maintain selectivity.

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A.J. DeRosset et al., Separation of C8Aromatics by Adsorption A.J. DeRosset et al., presented at the American Chemical Society, Los Angeles, CA Mar. 29-Apr. 2, 1971.

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