Separation of citric acid from fermentation broth with a neutral

Details Separation of citric acid from fermentation broth with a neutral Separation of citric acid from fermentation broth with a neutral

1986-12-18

1988-01-19

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562584, C07C 5142

Patent

active

047205792

ABSTRACT:
Citric acid is separated from a fermentation broth by using an adsorbent comprising a neutral, noniogenic, macroreticular, water-insoluble, crosslinked styrene-poly(vinyl)benzene and a desorbent comprising water and, optionally, acetone with the water. The pH of the feed is adjusted and maintained below the first ionization constant (pKa.sub.1) of citric acid to maintain selectivity.

REFERENCES:
patent: 3531463 (1970-09-01), Gustafson
patent: 3663467 (1972-05-01), Albright
patent: 3904684 (1975-09-01), Tsuda et al.
Johnson, J. Sci. Food Agric., vol. 33 (3), pp. 287-293.
Handbook of Chemistry & Physics, 53rd Edition, 1972-1973, CRC Press.

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