Chemistry: molecular biology and microbiology – Physical recovery methods
Patent
1994-05-09
1997-10-21
Kunz, Gary L.
Chemistry: molecular biology and microbiology
Physical recovery methods
210730, 436161, 5361231, 536124, 502232, B01D 1508, G01N 3048, C01B 3312
Patent
active
056795726
ABSTRACT:
Provided is a novel polysaccharide derivative having a main structure of the following formula (1) in which a polysaccharide or its derivative has been chemically bonded to the inner and outer surfaces of the pores of a porous carrier at the reducing terminal of the polysaccharide or polysaccharide derivative: ##STR1## Also provided are a method of producing the novel polysaccharide derivative in which a silane agent is chemically bonded to a porous carrier and thereafter a polysaccharide having a degree of polymerization from 11 to 500 or its derivative is further chemically bonded to surface treated carrier at the reducing terminal of the polysaccharide or its derivative, and a method of producing the novel polysaccharide derivative in which a polysaccharide having a degree of polymerization from 11 to 500 or its derivative is chemically bonded to a silane agent at the reducing terminal of the polysaccharide or its derivative and thereafter the polysaccharide derivative is further chemically bonded to a porous carrier. Further provided is a separating agent for chromatography containing the novel polysaccharide derivative. The novel polysaccharide derivative has excellent solvent resistance and is useful as a separating agent for chiral resolution of chiral compounds by chromatography. The methods of the present invention efficiently give the novel polysaccharide derivative.
REFERENCES:
patent: 4619970 (1986-10-01), Okamoto et al.
patent: 4818394 (1989-04-01), Okamoto et al.
patent: 4861872 (1989-08-01), Okamoto et al.
patent: 4912205 (1990-03-01), Okamoto et al.
patent: 5032277 (1991-07-01), Okamoto et al.
patent: 5051500 (1991-09-01), Elmore
patent: 5071978 (1991-12-01), Sau
patent: 5202433 (1993-04-01), Okamoto et al.
patent: 5371208 (1994-12-01), Kozulic
Elisabeth Kallin et al, "New Derivatization and Separation Procedures for Reducing Oligosaccharides", Glycoconjugate J. 1986 3, 311-319.
Yoshio Okamoto et al, "Tris(4-t-butylphenylcarbamate)s of Cellulose and Amylose as Useful Chiral Stationary Phases for Chromatographic Optical Resolution", Chemistry Letters (1989), pp. 715 to 718.
Patent Abstracts of Japan, vol. 12, No. 159, 14 May 1988 of JP-A-62 270602, 25 Nov. 1987, & Database WPI, Week 8802, Derwent Publications Ltd., London, GB; AN 009299.
Manssur Yalpani, "Polysaccharides", 1988, Elsevier, Amsterdam, pp. 294-297. Month not available.
S. Kim et al, "Copolymers of Depolymerized Cellulose Triacetate and Diisocyanates", vol. 7, 1979, New York, pp. 101-105. Month not available.
Akano Hirofumi
Enomoto Naoki
Kawamura Yoshiya
Ogasawara Yasushi
Ohishi Ryu
Daicel Chemical Industries Ltd.
Kunz Gary L.
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