Separation of blood coagulation factors with non-activating poly

Details Separation of blood coagulation factors with non-activating poly Separation of blood coagulation factors with non-activating poly

1978-08-15

1979-06-05

Levin, Stanford M.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Polymers from only ethylenic monomers or processes of...

260112B, 260122, 424101, 424177, 526 50, 526 522, 526 525, C08F 832, C07G 700

Patent

active

041574311

ABSTRACT:
Blood coagulation factors such as Factor VIII are separated from admixture with other blood proteins without producing activation of said coagulation factors by contacting with a water-insoluble, cross-linked polyelectrolyte copolymer of (a) C.sub.2-18 unsaturated monomer and (b) C.sub.4-12 unsaturated polycarboxylic acid or anhydride which is partially substituted at its free carboxyl or anhydride sites with amine-imides and in which substantially all the remaining free carboxyl or anhydride sites are blocked with alkoxyalkylamine to form alkoxyalkylimide units.

REFERENCES:
patent: 3157595 (1964-11-01), Johnson et al.
patent: 3340680 (1967-09-01), Fields et al.
patent: 3554985 (1971-01-01), Fields et al.
patent: 3555001 (1971-01-01), Wallis et al.
patent: 3651213 (1972-03-01), Wallis et al.
patent: 3655509 (1972-04-01), Fields et al.
patent: 3682881 (1972-08-01), Fekete et al.

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