Separation of an organic acid from a fermentation broth with an

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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C07C 5142

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050684191

ABSTRACT:
An organic acid is separated from a fermentation broth by using an adsorbent comprising a water-insoluble macroreticular or gel weakly basic anionic exchange resin possessing tertiary amine or pyridine functional groups or a strongly basic anionic exchange resin possessing quaternary amine functional groups. The resins are in sulfate form and have a cross-linked acrylic or styrene resin matrix. The organic acid is desorbed with water or dilute inorganic acid, e.g., sulfuric. The pH of the feed is maintained below the first ionization constant (pKa.sub.1) of the organic acid to obtain high selectivity.

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