Separation of alpha interferon receptor proteins and antibodies

Details Separation of alpha interferon receptor proteins and antibodies Separation of alpha interferon receptor proteins and antibodies

1990-05-03

1996-05-14

Cunningham, Thomas

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

4241981, 530350, 530351, 530395, 514 2, 514 8, A61K 3900, C07K 14715

Patent

active

055165150

ABSTRACT:
Two distinct alpha interferon receptor proteins have been separated and partially purified by antigen affinity chromatography and SDS-PAGE. These proteins are potentially useful as therapeutic agents. Antibodies against these proteins are potentially useful as diagnostic and therapeutic agents.

REFERENCES:
C. R. Faltynek, et al. PNAS 80: 3269-73, Jun. 1983, Characteriz. of an interferon receptor . . .
Hannigan, G. E. et al. Eur J. Biochem 157: 187-193. 1986. Differential human interferon . . .
Eid, P. et al. FEBS 156(1):157-160. Jun. 1983. Isolated interferon .alpha.-receptor complex . . . Traub, A et al. JBC 259(22): 13872-7. Nov. 1984. Purification and Properties . . .
Chemical Abstracts, vol. 99. Abstract No. 36944u, 1983.
Chemical Abstracts, vol. 105, Abstract No. 224075c, 1986.
Chemical Abstracts, vol. 101, Abstract No. 189489j, 1984.
Chemical Abstracts, vol. 101, Abstract No. 189491d, 1984.
Chemical Abstracts, vol. 104, Abstract No. 86869, 1986.
Chemical Abstracts, vol. 100, Abstract No. 21287x, 1981.
Chemical Abstracts, vol. 97, Abstract No. 214016m, 1982.

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