Separation medium

Details Separation medium Separation medium

1988-07-19

1989-07-25

Garvin, Patrick P.

Catalyst, solid sorbent, or support therefor: product or process

Solid sorbent

Organic

502402, 502403, B01J 2022

Patent

active

048513822

ABSTRACT:
A separation medium useful as an adsorbent of liquid chromatography for optical resolution of racemic mixtures is disclosed, which comprises a reversed phase support coated with an optically active amino acid derivative represented by formula (I): ##STR1## wherein R.sub.1 represents a straight or branched alkyl group having from 1 to 3 carbon atoms; and R.sub.2 and R.sub.3 each represents a straight or branched alkyl group having from 4 to 12 carbon atoms which may contain an aromatic group or an unsaturated alkyl group.
The separation medium is applicable to optical resolution of a wide range of DL-amino acids and exhibits excellent durability.

REFERENCES:
patent: 4324681 (1982-04-01), House
patent: 4525465 (1985-06-01), Someno et al.
patent: 4654322 (1987-03-01), Holbein et al.
patent: 4767670 (1988-08-01), Cox et al.
patent: 4793921 (1988-12-01), Hauck et al.

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