Radiant energy – Ionic separation or analysis – With sample supply means
Reexamination Certificate
2005-06-21
2005-06-21
Berman, Jack I. (Department: 2881)
Radiant energy
Ionic separation or analysis
With sample supply means
C210S198200, C210S296000
Reexamination Certificate
active
06909091
ABSTRACT:
The invention describes a new integrated separation and analysis system for analysis and separation of at least one sample component, comprising a mass sensitive detector (1) with ionization source (2), at least one mobile solid phase (3), at least one sample component (4), one transport system (5) where the mobile solid phase and the sample component are transported, and at least one transport fluid (6). The sample component is separated at the interface between the transport and the mass sensitive detector. Also, a method for analysis and separation of sample components is included, utilizing the mentioned integrated separation and analysis system. According to the method, the mobile solid phase and the sample are separated before the mass analyzer, and the sample components are transported towards the mass analyzer.
REFERENCES:
patent: 6027890 (2000-02-01), Ness et al.
patent: WO 93/20435 (1993-10-01), None
Hjerten; “Free Zone Electrophoresis”; Institute of Biochemistry, University of Uppsala, Sweden, pp. 122-219, (1967).
Monning et al.; “Capillary Electrophoresis.”; Analytical Chemistry, vol. 66, No. 12, pp. 280-314, (1994).
Terabe et al.; “Electrokinetic Chromatography With Micellar Solution and Open-Tubular Capillary”; Analytical Chemistry, vol. 57, No. 4, pp. 834-841, (1985).
Mazzeo; “Micellar Electrokinetic Chromatography”; Handbook of Capillary Electrophoresis, Chapter 2, pp. 49-73, (1997).
Knox et al.; “Miniaturisation in Pressure and Electroendosmotically Driven Liquid Chromatography: Some Theoretical Considerations”; Chromatographia, vol. 24, pp. 135-143, (1987).
Knox et al.; “Electrochromatography in Packed Tubes Using 1.5 to 50 μm Silica Gels and Ods Bonded Silica Gels”; Chromatograpia, vol. 32, No. 7/8, pp. 317-328, (1991).
Valtcheva et al.; “Chiral Separation of β-Blockers by High=-Performance Capillary Electrophoresis Based on Non-Immobilized Cellulase as Enantioselective Protein”; Journal of Chromatography, vol. 638, pp. 263-267, (1993).
Amini et al.; “Principle and Applications of the Partial Filling Technique in Capillary Electrophoresis”; Chromatographia, vol. 50, No. 7/8, pp. 497-506, (1999).
Schweitz et al.; “Molecularly Imprinted Microparticles for Capillary Electrochromatographic Enantiomer Separation of Propranolol”; Analyst, vol. 125, pp. 1899-1901, (2000).
Dole et al.; “Molecular Beams of Macroions”; The Journal of Chemical Physics, vol. 49, No. 5, pp. 2240-2249, (1968).
Thomson et al.; “Field Induced Ion Evaporation From Liquid Surfaces at Atmospheric Pressure”; J. Chem. Phys. vol. 71, No. 11, pp. 4451-4463, (1979).
Yamashita et al.; “Electrospray Ion Source. Another Variation on the Free-Jet Theme”; The Journal of Physical Chemistry, vol. 88, No. 20, pp. 4451-4459, (1984).
Santesson et al.; “Airborne Cell Analysis”; Analytical Chemistry, vol. 72, No. 15, pp. 3412-3418, (2000).
Chen et al.; “Macroporous Photopolymer Frits for Capillary Electrochromatography”; Analytical Chemistry, vol. 72, No. 6, pp. 1224-1227, (2000).
Behnke et al.; “Fluorescence Imaging of Frit Effects in Capillary Separations”; Electrophoresis, vol. 21, pp. 3102-3108, (2000).
Nilsson Staffan
Schweitz Leif
Spégel Peter
Viberg Peter
Berman Jack I.
Finnegan Henderson Farabow Garrett & Dunner LLP
Nanosep AB
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