Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1998-03-23
2000-10-03
Priebe, Scott D.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 43525411, 435325, 4353201, 536 231, 536 232, 536 237, C07H 2100, C21N 121, C21N 1531, C21N 1563
Patent
active
061271470
ABSTRACT:
The invention provides histidine kinase polypeptides and DNA (RNA) encoding histidine kinase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing histidine kinase polypeptides to screen for antibacterial compounds.
REFERENCES:
SwissProt Submission, Accession No. P27668, Direct Submission.
Island, et al, "Structure and Function of the uhp Genes for the Sugar Phosphate Transport System in Escherichia coli and Salmonella typhimurium", Journal of Bacteriology, vol. 174, No. 9, pp. 2754-2762, May 1992.
Ngo et al., "Computational complexity, protein structure prediction, and the Levinthal paradox", in The Protein Folding Problem and Tertiary Structure Prediction, Merz et al. (eds.), Birkhauser Boston: Boston, MA, pp. 433 and 492-495, 1994.
Rudinger, "Characteristics of the amino acid as componants of a peptide hormone sequence", in Peptide Hormones, Parsons (eds.), University Park Press: Baltimore, MD, pp. 1-7, Jun. 1976.
Walderhaug et al. "KdpD and KpdE, proteins that control expression of the kpdABC operon, are members of the two-component sensor-effector class of regulators", J. Bacteriol. 174 (7): 2152-2159, Apr. 1992.
Deibert Thomas S.
Gimmi Edward R.
King William T.
Priebe Scott D.
SmithKline Beecham Corporation
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