Sensor for components of a liquid mixture

Details Sensor for components of a liquid mixture Sensor for components of a liquid mixture

1982-10-22

1985-10-08

Cohen, Lee S.

Surgery

Truss

Pad

204403, 204415, A61B 500

Patent

active

045453829

ABSTRACT:
A sensor electrode to detect one or more components in a liquid mixture comprises an electrically conductive material having at least an an external surface, the combination of an enzyme catalytic for a reaction of the desired component, and a mediator compound which transfers electrons from the enzyme to the electrode when such catalytic activity takes place. It can be used as an in vivo glucose sensor either with a silver electrode coated with e.g. glucose oxidase and a polyviologen as the mediators, or with a particulate carbon electrode, glucose oxidase and chloranil or fluoranil as mediator. Another system is to use bacterial glucose dehydrogenase or glucose oxidase as the enzyme and/or ferrocene or a ferrocene derivative as the mediators compound to give electrodes with improved linearity, speed of response and insensitivity to oxygen.

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