Sensor for antigen-antibody reactions

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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356306, 356317, 356318, 356337, 356338, 356441, 356244, 356246, 422 681, 422 8205, 422 8208, 435 733, 435 734, 435 735, 435 34, 435 35, 4352872, 435291, 435296, 435808, 4352887, 436164, 436172, 436514, 436805, G01N 33569, G01N 3358, G01N 3360

Patent

active

055433294

ABSTRACT:
A multi-purpose on-line or field-portable system and method for monitoring the presence and concentration of selected antigen-antibody reactions singly or in combination that result from the presence of specific microorganisms or free antigens present or suspended in aqueous solutions, during a given time period. The detection system comprises a detection column and two sensors mounted around the J-shaped detection column. Each sensor consists of an electromagnetic radiation source and an appropriate detector for the electromagnetic radiation. The reacted analyte tends to accumulate at the sensor located in the curve of the J-shaped detection column. The lower sensor continually nulls against the upper sensor to subtract any optical effects due to non-reactants in the aqueous process or environmental stream. The response from the detector sensors drive an electric circuit, which provides an output signal. In the on-line automatic version, the signal can drive elements of a process system by switching automated valves.

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patent: 4652530 (1987-03-01), Rothman et al.
patent: 4908676 (1990-03-01), Bedell et al.

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