Electrolysis: processes – compositions used therein – and methods – Electrolytic analysis or testing – For ph
Patent
1998-01-14
1999-09-14
Bell, Bruce F.
Electrolysis: processes, compositions used therein, and methods
Electrolytic analysis or testing
For ph
2057825, 205775, 422 8201, 422 8202, 422 98, 436150, 436151, 204406, 204415, 204418, 73 232, 73 2331, 73 2334, 7333505, 324691, 324693, 338 7, 338 13, 338 14, G01N 2726
Patent
active
059518464
ABSTRACT:
Chemical sensors for detecting analytes in fluids comprise first and second conductive elements (e.g. electrical leads) electrically coupled to and separated by a chemically sensitive resistor which provides an electrical path between the conductive elements. The resistor comprises a plurality of alternating nonconductive regions (comprising a nonconductive organic polymer) and conductive regions (comprising a conductive material) transverse to the electrical path. The resistor provides a difference in resistance between the conductive elements when contacted with a fluid comprising a chemical analyte at a first concentration, than when contacted with a fluid comprising the chemical analyte at a second different concentration. Arrays of such sensors are constructed with at least two sensors having different chemically sensitive resistors providing dissimilar such differences in resistance. Variability in chemical sensitivity from sensor to sensor is provided by qualitatively or quantitatively varying the composition of the conductive and/or nonconductive regions. An electronic nose for detecting an analyte in a fluid may be constructed by using such arrays in conjunction with an electrical measuring device electrically connected to the conductive elements of each sensor.
REFERENCES:
patent: 3045198 (1962-07-01), Dolan et al.
patent: 4542640 (1985-09-01), Clifford
patent: 4631952 (1986-12-01), Donaghey
patent: 4759210 (1988-07-01), Wohltjen
patent: 4855706 (1989-08-01), Hauptly
patent: 4907441 (1990-03-01), Shurmer
patent: 4992244 (1991-02-01), Grate
patent: 5045285 (1991-09-01), Kolesar, Jr.
patent: 5120421 (1992-06-01), Glass et al.
patent: 5256574 (1993-10-01), Neuberger et al.
patent: 5417100 (1995-05-01), Miller et al.
patent: 5512882 (1996-04-01), Stetter et al.
patent: 5571401 (1996-11-01), Lewis et al.
patent: 5623212 (1997-04-01), Yamanaka
patent: 5654497 (1997-08-01), Hoffheins et al.
patent: 5675070 (1997-10-01), Gelperin
patent: 5698089 (1997-12-01), Lewis et al.
patent: 5788833 (1998-08-01), Lewis et al.
Dickinson et al., "A chemical-detecting system based on a cross-reactive optical sensor array," Nature, 382(22):697-699 (1996) No month available.
Dickinson, et al., "Generating Sensor Diversity through Combinatorial Polymer Synthesis," Analytical Chemistry, 69(17):3413-3418 (1997) No month available.
Johnson et al., "Identification of Multiple Analytes Using an Optical Sensor Array and Pattern Recognition Neural Networks," Analytical Chemistry, 69(22):4641-4648 (1997) No month available.
Lewis, "The Caltech Electronic Nose Project," Engineering & Science, 3:3-13 (1996) No month available.
Lonergan et al., " Array-Based Vapor Sensing Using Chemically Sensitive, Carbon Black--Polymer Resistors," Division of Chemistry and Chemical Engineering, California Institute of Technology, XP-002078727, Chemical Material, 8:2298-2312 (1996) No month available.
Lonergan et al., "Array-Based Vapor Sensing Using Chemically Sensitive, Polymer Composite Resistors," Division of Chemistry and Chemical Engineering, California Institute of Technology, XP-002078726, pp. 583-631 No month/yr. available.
White et al., "Rapid Analyte Recognition in a Device Based on Optical Sensors and the Olfactory System," Analytical Chemistry, 68(13):2191-2202 (1996) No month available.
Andrieux, Claude, et al., "Observation of the Cation Radicals of Pyrrole and of Some Substituted Pyrroles in Fast-Scan Cyclic Voltammetry," Standard Potentials and Lifetimes, J. Am. Chem. Soc., 112, pp. 2439-2440.
Barlett, P.N., et al., "Electrochemical Deposition of Conducting Polymers onto Electronic Substrates for Sensor Applications," Sensors and Actuators A, A21-A23, pp. 911-914 (1990) No month available.
Bidan, G. et al., "Polypyrrole and poly(N-methylpyrrole) films doped with Keggin-type heteropolyanions: preparation and properties," J. Electroanal. Chem., 251, pp. 297-306 (1988).
Charlesworth, John, et al., "Mechanistic Studies on the Interactions between Poly(pyrrole) and Organic Vapors," J. Phys. Chem., 97, pp. 5418-5423 (1992) No month available.
Corcoran, P., et al., "Integrated tin oxide sensors of low power consumption for use in gas and odour sensing," Sensors and Actuators B, 15-16, pp. 32-37 (1993) No month available.
DeVries, Steven, et al., "Synaptic Circuitry of the Retina and Olfactory Bulb," Cell/Neuron, 72/10 (Suppl) pp. 139-149 (1993) No month available.
Diaz, A.F., et al., "Electrooxidation of Aromatic Oligomers and Conducting Polymers," J. Electr. Chem., 121, pp. 355-361 (1981) No month available.
Gardner, Julian W., et al., "Integrated Tin Oxide Odour Sensors," Sensors and Actuators B, 4, pp. 117-121 (1991) No month available.
Gardner, Julian W., et al., "Application of an electronic nose to the discrimination of coffees," Sensors and Actuators B, 6, pp. 71-75 (1992) No month available.
Gardner, Julian W., et al., "Design of Conducting Polymer Gas Sensors: Modelling and Experiment," Synthetic Metals, vol. 55-57, pp. 3665-3670 (1993) No month available.
Gardner, Julian W., et al., "Detection of vapours and odours from a multisensor array using pattern-recognition. Part 2. Artificial Neural Networks," Sensors and Actuators B, 9, pp. 9-15 (1992) No month available.
Gardner, Julian W., et al., "Detection of vapours and odours from a multisensor array using pattern-recognition Part 1. Principal Component and Cluster Analysis," Sensors and Actuators B, 4, pp. 109-115 (1991) No month available.
Gardner, Julian W., et al., "A multisensor system for beer flavor monitoring using an array of conducting polymer and predictive classifiers," Sensors and Actuators B, 18-19, pp. 240-243 (1994) No month available.
Gardner, Julian W., et al., "A brief history of electronic noses," Sensors and Actuators B, 18-19, pp. 211-220 (1994) No month available.
Grate, Jay W., et al., "Solubility interactions and the design of chemically selective sorbent coatings for chemical sensors and arrays," Sensors and Actuators B, 3, pp. 85-111 (1991) No month available.
Grate, Jay W., et al., "Smart Sensor System for Trace Organophosphorous and Organosulfur Vapor Detection Employing a Temperature-Controlled Array of Surface Acoustic Wave Sensors, Automated Sample Preconcentration and Pattern Recognition," Anal. Chem., 65, pp. 1868-1881 (1993) No month available.
Kanzawa, K.K., et al., "Electrical Properties of Pyrrole and its Copolymers," Synthetic Metals, 4, 119-130 (1981) No month available.
Kauer, John S., "Contributions of topography and parallel processing to odor coding in the vertebrate olfactory pathway," TINS, vol. 14, No. 2, pp. 79-85 (1991) No month available.
Kaufman, J.H., et al., "Evolution of Polaron States into Bipolarons in Polypyrrole," Physical Review Letters, vol. 53, No. 19, pp. 1005-1008 (1984) No month available.
Lancet, Doron, et al., "Olfactory receptors," Current Biology, vol. 3, No. 10, pp. 668-674 (1993) No month available.
Lundstrom, I., et al., "Artificial `Olfactory` images from a chemical sensor using a light-pulse technique," Nature, vol. 352, pp. 47-50 (1991) No month available.
Morris, A.C., et al., "The System Ethanol-Methanol at 40.degree. C.," Canadian Journal of Research, vol. 20, Sec. B, pp. 207-211 (1942) No month available.
Pearce, Timothy C., et al., "Electronic Nose for Monitoring the Flavour of Beers," Analyst, vol. 118, pp. 371-377 (1993) No month available.
Reed, Randall R., "Signaling Pathways in Odorant Detection," Neuron, vol. 8, pp. 205-209 (1992) No month available.
Salmon, M., et al., "A Chemical Route to Pyrrole Polymer Films," Journal of Polymer Science, 20-3, pp. 187-193 (1982) No month available.
Shurmer, Harold V., et al., "Odour Discrimination with an electronic nose," Sensors and Actuators B, 8, pp. 1-11 (1992) No month available.
Shurmer, Harold V., et al., "Integrated Arrays of Gas Sensors Using Conducting Polymers with Molecular Sieves," Sensors and Actuators B, 4, pp. 29-33 (1991) No month available.
Stetter, J.R., et al, "Detection of Hazardous Gases and Vapors: Pattern Recognition Analysis of Data from an Electrochemical Sensor Array," Anal. Chem., 58, pp. 860-866 (19
Freund Michael S.
Lewis Nathan S.
Bell Bruce F.
California Institute of Technology
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