Sensor and method for measuring the areal density of...

Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample

Reexamination Certificate

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C422S050000, C422S068100, C422S082010, C435S006120, C435S007100, C435S287100, C435S287200, C435S287900, C435S288300, C435S288400, C436S524000, C436S525000, C436S526000, C210S222000

Reexamination Certificate

active

07048890

ABSTRACT:
Method and device for magnetic detection of binding of biological molecules on a biochip in which a magnetoresistive sensor device measures an areal density of magnetic nanoparticles on a micro-array, the magnetic nanoparticles being directly or indirectly coupled to a target sample. The magnetoresistive sensor device includes a substrate having attached thereto binding sites able to selectively bind the target sample, and a magnetoresistive sensor for detecting the magnetic field of the nanoparticles coupled to the target sample. The magnetoresistive sensor includes a plurality of magnetoresistive sensing elements, the width and length dimensions of which are at least a factor10or more, preferably a factor100or more larger than the diameter of the nanoparticles.

REFERENCES:
patent: 5021736 (1991-06-01), Gonsalves et al.
patent: 5411814 (1995-05-01), Jin et al.
patent: 5412087 (1995-05-01), McGall et al.
patent: 5447781 (1995-09-01), Kano et al.
patent: 5569544 (1996-10-01), Daughton
patent: 5739990 (1998-04-01), Ravipati et al.
patent: 5981297 (1999-11-01), Baselt
patent: 6592820 (2003-07-01), Hardman et al.
patent: 6844202 (2005-01-01), Prinz et al.
patent: 2002/0119470 (2002-08-01), Nerenberg et al.
patent: 2004/0033627 (2004-02-01), Aytur et al.
patent: 2004/0219695 (2004-11-01), Fox
patent: WO 200114591 (2001-03-01), None
Baibich, M.N. et al., “Giant magnetoresistance of (001)Fe/(001)Cr magnetic superlattices”, 1988, Physical Review Letters, vol. 61, pp. 2472-2475.
Baselt, D.R. et al. “A biosensor based on magnetoresistance technology”, 1998, Biosensors & Bioelectronics, vol. 13, pp. 731-739.
Edelstein, R.L. et al. “The BARC biosensor applied to the detection of biological warfare agents”, 2000, Biosensors & Bioelectronics, vol. 14, pp. 805-813.
Schotter, J. et al. “Comparison of a prototype magnetoresistive biosensor to standard fluorescent DNA detection”, 2004, Biosensor & Bioelectronics, vol. 19, pp. 1149-1156.
Smith, N. et al., “A high-sensitivity magnetoresistive magnetometer”, 1991, Journal of Applied Physics, vol. 69, pp. 5082-5084.
Vassiliou, J.K. et al., “Magnetic and optical properties of gama-Fe203 nanocrystals”, 1993, Journal of Applied Physics, vol. 73, pp. 5109-5116.

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