Sensor and detecting method

Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample

Reexamination Certificate

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Details

C422S050000, C422S068100, C422S082020, C422S082030, C436S149000, C436S150000, C436S806000

Reexamination Certificate

active

11048749

ABSTRACT:
A sensor is provided for detecting a target substance in a sample by detecting a product formed in the presence of an enzyme and an enzyme substrate. The sensor comprises two or more working electrodes, a first capturing molecule immobilized on the working electrodes, and a current-detector for detecting a current value flowing through at least one of the working electrodes. The sensor also comprises a target substance detection means having an arithmetic unit for determining an amount of the target substance in the sample on the basis of the current value detected by the current-detector in a specified period of time, and a crosstalk detecting electrode arranged between the working electrodes for detecting a crosstalk between the working electrodes. The specified period of time is a time necessary for the current value through the crosstalk detecting electrode to show a particular change.

REFERENCES:
patent: 5286362 (1994-02-01), Hoenes et al.
patent: 5399256 (1995-03-01), Bohs et al.
patent: 2003/0082601 (2003-05-01), Dill
patent: 2007/0004019 (2007-01-01), Hatakeyama et al.
Kojima et al., “Electrochemical protein chip with arrayed immunosensors with antibodies immobilized in a plasma-polymerized film”, Mar. 1, 2003, Anal. Chem. vol. 75, pp. 1116-1122.

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