Sensitized sheep stroma immunoassay for rheumatoid factor

Chemistry: physical processes – Physical processes – Crystallization

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23915, 422 56, 424 12, G01N 3354

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active

042820022

ABSTRACT:
A new and immunochemically useful reagent is disclosed for the detection of rheumatoid factors (RF) in human blood, plasma, serum or synovial fluid in agglutination reactions, together with a new clinical diagnostic test and test slide using said reagent. The reagent consists essentially of a supply of red cell stroma having absorbed upon their surface a sensitizing agent. Preferably the red cell stroma is sheep red cell stroma, and most preferably the sensitizing agent is rabbit anti-sheep red cell globulin.

REFERENCES:
patent: 3548051 (1970-12-01), Dingwall
patent: 3565987 (1971-02-01), Schuurs
patent: 3594466 (1971-07-01), Guffroy
patent: 3654083 (1972-04-01), Schuurs
patent: 3655838 (1972-04-01), Price et al.
patent: 3655874 (1972-04-01), van Hell
patent: 3666421 (1972-05-01), Price
patent: 3689632 (1972-09-01), Mizushima et al.
patent: 3714344 (1973-01-01), Brown
patent: 3714345 (1973-01-01), Hirata
patent: 3826613 (1973-12-01), Huber
patent: 3843777 (1974-07-01), Parikh et al.
patent: 3862302 (1975-01-01), Price et al.
patent: 3899298 (1975-08-01), Szczesniak
patent: 3903254 (1975-09-01), Dahlgren et al.
patent: 3905767 (1975-09-01), Morris et al.
patent: 4053284 (1977-10-01), Posch
patent: 4055394 (1977-10-01), Friedmann et al.
patent: 4062935 (1975-12-01), Masson et al.
Hepler, Manual of Clinical Laboratory Methods, 4th ed. at 222 (Thomas 1966).
Singer and Plotz, "The Latex Fixation Test", American J. of Med. 21 at 888-892 (1956).
Bartfield, "Distribution of Rheumatoid Factor Activity in Non-rheumatoid States", Annals, New York Academy of Sciences at 30-40 (1970 (?)).
I. Davidson, "Serologic Diagnosis of Infectious Mononucleosis", J. Amer. Med. Asso. 108(4) at 289-295 (1937).
Waaler, "On the Occurrence of a Factor in Human Serum Activating the Specific Agglutination of Sheep Blood Corpuscles", Acta Path. Micro Biol. Scand. 17 at 172-188 (1940).
Rose et al., Proc. Soc. Exp. Biol. Med. 68 at 1 et seq (1948).
Heller, et al., "The Hemaaglutination Test for Rheumatoid Arthritis", Part II, J. Immun. 72 at 66-78 (1954) and Id, Pt. I, J. Immun. 69 at 27-40 (1952).
E. Engvall & P. Perlmann, "Enzyme-linked Immunosorbent Assay, Elisa", J. Immunology 109(1) at 129-135 (1972).
John S. Cowdery et al., "A Radioimmunoassay for Human Antigen-Antibody Complexes in Clinical Material", J. Immunology 114(1) at 5-9 (1975).

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