Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1987-09-09
1988-05-03
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
A61K 3170
Patent
active
047420502
ABSTRACT:
Method of sensitizing hypoxic tumor cells to radiotherapy and chemotherapy by contacting the cells or the vasculature thereof with an aqueous dispersion of an oxygen carrying perfluoro compound and a dispersant for the compound, and sensitizing chemotherapeutic and protective compositions therefor.
REFERENCES:
patent: 3453333 (1969-07-01), Litt et al.
patent: 3778381 (1973-12-01), Rosano et al.
patent: 3828085 (1974-08-01), Price et al.
patent: 4241060 (1980-12-01), Smithen
patent: 4282232 (1981-08-01), Agrawal
patent: 4325972 (1982-04-01), Geyer et al.
patent: 4366169 (1982-12-01), White
"Radiopaque Applications of Brominated Fluorocarbon Compounds in Expermimental Animals and Human Subjects," D. M. Long et al., appearing in Biochemistry Involving Carbon-Fluorine Bonds, edited by R. Filler, ACS Symposium Series No. 28, 171-189, (1976).
Chemical Abstracts, vol. 87, No. 23, Dec. 5, 1977, p. 278, No. 181618x, Columbus, Ohio, U.S.A., T. Matsumoto et al.: "Role on Oncotic Agents in Saving Effect of Perfluorochemical Emulsions in Hemodilution" Chem. Pharm. Bull., 1977, 25 (9), 2163-2171.
Chemical Abstract, vol. 79, No. 13, Oct. 1, 1973, p. 45, No. 73792a, Columbus, Ohio, U.S.A., R. Esaki et al.: "Sensitivity of Anticancer Drugs and Their Concentration in Tissues" Advan. Antimicrob. Antineoplastic Chemother. Proc. Int. Congr. Chemother., 7th 1971, (Pub. 1972), 2, 383-386.
Chemical Abstracts, vol. 97, No. 11, Sep. 13, 1982, p. 55, No. 84920p, Columbus, Ohio, U.S.A., T. Kokunai et al.: "Effect of Perfluorochemicals on BCNU Chemotherapy in a Rat Brain-Tumor Model" Brain Nerve, 1982, 34(6), 609-615.
Chemical Abstracts, vol. 97, No. 23, 6th Dec. 1982, pp. 26, 27, No. 192822a, Columbus, Ohio, U.S.A., J. Neurosurg., 1982, 57(4), 467-471.
Chemical Abstracts, vol. 96, No. 12, Mar. 1982, pp. 400, 401, No. 91568n, Columbus, Ohio, U.S.A., A. N. Markina et al.: "Emulsifying Capacity of Sodium Deoxycholate in Regards to Perfluorocarbons in the Aqueous Phase" Perftorirovannye Uglerody Biol. Med. 1980, 67-75.
The Merck Index, 1976, pp. 359, 371, 782, 1282.
Goodman Robert L.
Moore Robert E.
Yuhas, deceased John M.
Adamantech, Inc.
Friedman Stanley J.
Hess J. Edward
Johnson Donald R.
LandOfFree
Sensitization of hypoxic tumor cells and control of growth there does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Sensitization of hypoxic tumor cells and control of growth there, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sensitization of hypoxic tumor cells and control of growth there will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1506343