Sensitive tests for malignancies based on DNA detection

Details Sensitive tests for malignancies based on DNA detection Sensitive tests for malignancies based on DNA detection

1982-06-17

1984-12-25

Padgett, Ben R.

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

Utilizing isolate of tissue or organ as binding agent

436804, 436813, 436815, 435 6, 4351723, 536 27, 935 19, C12N 1500, C07H 1512, G01N 3350

Patent

active

044904720

ABSTRACT:
An improved, more convenient, more sensitive test for detection of certain malignancies in human and animal subjects is disclosed. Sera from test subjects is mixed with labeled DNA in the presence of an enzyme-conjugated resin. Sera from normal and cancerous subjects react differently with the resin, permitting a diagnosis of the subject.

REFERENCES:
patent: 4358535 (1982-11-01), Falkow et al.

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