Sensitive on line assay of chromatographic effluent

Chemistry: analytical and immunological testing – Automated chemical analysis – With a continuously flowing sample or carrier stream

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422 52, 422 53, 422 66, 422 67, 4352873, 4352886, 4352887, 436 46, 436 47, 436164, 436172, G01N 3508

Patent

active

055916449

ABSTRACT:
A method for on-line assay in column chromatography of a property that requires appreciable time for sensitive measurement has the steps of separating the effluent into discrete fractions at equal time intervals, sequentially passing each fraction through each of a series of detectors, while preventing each fraction from mixing with another; and, for each fraction, calculating the assay from the information provided by each detector during the time interval the fraction passed through it.

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