Sensitive method for localizing chromosomal breakpoints

Details Sensitive method for localizing chromosomal breakpoints Sensitive method for localizing chromosomal breakpoints

1993-12-02

1996-12-10

Elliott, George C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, 536 2431, 536 2433, C12Q 168, C12P 1934, C07H 2104

Patent

active

055829732

ABSTRACT:
A sensitive method for identifying chromosomal breakpoints flanked by repeat sequences, through amplification by polymerase chain reaction, is described. The application of the method to the detection of Burkitt's lymphoma cells is demonstrated.

REFERENCES:
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4701409 (1987-10-01), Croce

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