Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1997-04-17
1999-10-12
Ketter, James
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
536 241, 536 243, 536 2431, A61K 3500
Patent
active
059655437
ABSTRACT:
Recombinant polynucleotides have expression control sequences that have a senescence responsive element and a minimal promoter, and which are operatively linked to a heterologous nucleotide sequence. The molecules are useful for achieving high levels of expression of genes in senescent cells. Methods of inhibiting expression of genes in senescent cells also are provided.
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Campisi Judith
Testori Alessandro
Geron Corporation
Hughes Melya J.
Kaster Kevin R.
Ketter James
Storella John R.
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