Seneca Valley virus based compositions and methods for...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C435S235100, C424S093100

Reexamination Certificate

active

08039606

ABSTRACT:
The present invention relates to a novel RNA picornavirus that is called Seneca Valley virus (“SVV”). The invention provides isolated SVV nucleic acids and proteins encoded by these nucleic acids. Further, the invention provides antibodies that are raised against the SVV proteins. Because SVV has the ability to selectively kill some types of tumors, the invention provides methods of using SVV and SVV polypeptides to treat cancer. Because SVV specifically targets certain tumors, the invention provides methods of using SVV nucleic acids and proteins to detect cancer. Additionally, due to the information provided by the tumor-specific mechanisms of SVV, the invention provides methods of making new oncolytic virus derivatives and of altering viruses to have tumor-specific tropisms.

REFERENCES:
patent: 5708157 (1998-01-01), Jacobs et al.
patent: 6531136 (2003-03-01), Studdert et al.
patent: 7638318 (2009-12-01), Hallenbeck et al.
patent: 2003/0165820 (2003-09-01), Day et al.
patent: WO-99/08692 (1999-02-01), None
patent: WO-02/103060 (2002-12-01), None
patent: WO-2005/030139 (2005-04-01), None
Adachi, M. et al., “Destruction of human retinoblastoma after treatment by the E variant of encephalomyocarditis virus,” Journal of Neuro-Oncology May 2006, vol. 77, No. 3, May 2006, pp. 233-240.
Bakonyi, T., et al., “Complete genome analysis and molecular characterization of usutu virus that emerged in Austria in 2001 Comparison with South Africa Strain SAAR-1776 and other flavivirus”, Virology, Oct. 2004, vol. 328, pp. 301-310.
International Search Report and Written Opinion issued for International Patent Application No. PCT/US2006/009142, 2007.
International Search Report and Wrtten Opinion issued for International Patent Application No. PCT/US2006/039523, 2007.
Supplementary European Search Report issued for European Patent Application No. EP 04 78 9044, 2007.
Cox, S.J. et al., “Protection against direct-contact challenge following emergency FMD vaccination of cattle and the effect on virus excretion from the oropharynx,” Vaccine 23 (2005) 1106-1113.
Database UniProt [Online] May 1, 2000, “Polyprotein.” retrieved from EBI accession No. UNIPROT: Q9QCE4, Database accession No. Q9QCE4, positions 654-664 and 1580-1610.
Database UniProt [Online] Oct. 1, 2002, “Polyprotein.” retrieved from EBI accession No. UNIPROT: Q8JW41, Database accession No. Q8JW41, positions 654-664 and 1580-1610.
Gromeier, M.M., et al., Intergenic poliovirus recombinants for the treatment of malignant glioma, PNAS, Jun. 2000, vol. 97, No. 12, pp. 6803-6808.
Halet et al., J. Gene. Virol. 2008, vol. 89, pp. 1265-1275.
Hernandez, J. Virol, 2002, vol. 74(9), pp. 4220-4228.
Huang, T., et al., “Oncolysis of heepatitis Metastasis of Colorectal Cancer by Recombinant Vesicular Stomatitis Virus in Ummune-Competent Mice”, Molecular Therapy, Sep. 2003, vol. 8, No. 3, pp. 424-440.
Kitamura et al., Proc. Natl. Acad. Sci. U.S.A. 1980, vol. 77, No. 6, pp. 3196-3200.
Marvil et al., J. Gene. Virol. 1999, vol. 80 (pt.3), pp. 653-662.
Mullen, T.J., et al., “Viral Oncolysis”, The Oncologist, Apr. 2002, vol. 7, pp. 106-119.
NC0039 published by Marvil et al. on 1999.
Russel, S.J., “RNA Viruses as virotherapy agents”, Cancer Gene Therapy, Nov. 2002, vol. 9, pp. 961-966.
Smith, M. et al., “Bovine enterovirus as an oncolytic virus: Foetal calf serum facilities its infection of human cells,” International Journal of Molecular Medicine, vol. 10, No. 1, Jul. 2002, pp. 49-53.
Spryrou, V., et al., “Treansmission and pathogenecity of encephalomycardititis virus (EMCV) a moong rats”, Vet. Res. Jan.-Feb. 2004, vol. 35, pp. 113-122.
Office Action dated Jun. 28, 2011 for corresponding Canadian Patent Application No. 2,540,177.

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