Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1976-02-13
1977-06-14
Schwartz, Gerald A.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
2603067C, A61K 3143, C07D49980
Patent
active
040298051
ABSTRACT:
Compounds represented by the formula ##STR1## wherein A is ##STR2## R is hydrogen, substituted or unsubstituted lower alkenyl or alkyl of 1 to 8 carbon atoms in the alkyl chain, phenyl or substituted phenyl, R.sub.1 is phenyl, substituted phenyl or lower alkyl substituted with phenyl, hydrates thereof, and
Pharmaceutically acceptable basic salts of said compounds or hydrates, useful as antibacterial therapeutic agents in the treatment of infectious diseases caused by Gram-positive and Gram-negative bacteria, particularly Gram-negative bacteria and particularly advantageous because of their stability in aqueous solution are disclosed.
Emodi Alexander S.
Newmark Harold Leon
Scialpi Leonard Joseph
Hoffmann-La Roche Inc.
Leon Bernard S.
Rosen Gerald S.
Schwartz Gerald A.
Welt Samuel L.
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