Semiconductor based excitation illuminator for fluorescence and

Optics: measuring and testing – By shade or color – With color transmitting filter

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Details

356317, 356318, 2504581, 2504611, G01N 2164

Patent

active

061542822

ABSTRACT:
Apparatus for exciting a fluorescent or phosphorescent molecule applied to a specimen in a microscope, the molecule having a known excitation wavelength, comprises a semiconductor light source capable of emitting an output light within a preselected wavelength band correlated with the excitation wavelength of the molecule, an electronic controller coupled to the light source for controlling the intensity of the output light, and an optical system for converting the output light into an excitation beam having a pre-selected distribution of light flux suitable for illuminating the specimen. The semiconductor light source is preferably a light emitting diode or superluminescent diode. The subject invention provides for a fluorescence excitation illuminator having a long lifetime and relatively low cost. Intensity modulation or attenuation can be achieved electronically, without the need for shutters.

REFERENCES:
patent: 4643550 (1987-02-01), Kitagawa et al.
patent: 4852985 (1989-08-01), Fujihara et al.
patent: 5489771 (1996-02-01), Beach et al.
patent: 5736410 (1998-04-01), Zarling et al.

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