Semi-permeable capillary assay device

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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422 56, 422 57, 422 58, 422101, 435 792, 435 793, 435 794, 435810, 435975, 436164, 436514, 436518, 436524, 436525, 436528, 436531, 436533, 436534, 436536, 436541, 436805, 436808, 436810, G01N 33543, G01N 33546, G01N 33553

Patent

active

054749026

ABSTRACT:
A method and a device for performing an assay in order to detect or determine the amount of an analyte in a test liquid, wherein bound and unbound reactants can be separated, comprising a capillary canal for liquid transport that is at least partly bordered by a semi-permeable layer, wherein during performance of an assay a movable solid phase material bearing a ligand capable of binding the analyte or binding a reactant for the analyte is within the capillary channel adjacent to the semi-permeable layer, said semi-permeable layer having pores that are sufficiently small to prevent the passage of the movable solid phase material and sufficiently large to permit passage of unbound reactants there through.

REFERENCES:
patent: 4920046 (1990-04-01), McFarland et al.
patent: 4943522 (1990-07-01), Eisinger et al.

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