Semi-interpenetrating polymer network scar treatment sheeting, p

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Wearing apparel – fabric – or cloth

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424443, 424444, 424445, A61F 1300

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active

059809230

ABSTRACT:
Elastomeric sheeting materials are described which are formed from the process of (1) creating a membrane comprising a semi-interpenetrating polymer network ("IPN") of polytetrafluoroethylene ("PTFE") and polydimethylsiloxane ("PDMS") by causing a matrix of PDMS to be formed in situ with a matrix of PTFE; (2) causing a surface of substantially pure PDMS to be formed on at least one side thereof; (3) allowing said PDMS compositions to vulcanize; and (4) converting said structure into useful shapes suitable for application to anatomical areas of the body. The product of the process is suitable for the treatment of dermatologic scars, such as those associated with traumatic or surgical injuries of the skin. The pure PDMS layer provides desired therapeutic effects. The semi-IPN membrane provides improved physical integrity, durability, and elastic behavior in comparison to prior art. The combined structure has increased compliancy, a thinner profile, and improved patient comfort features in comparison to existing products.

REFERENCES:
patent: 4832009 (1989-05-01), Dillon
patent: 4945125 (1990-07-01), Dillon et al.
patent: 4983395 (1991-01-01), Chang et al.
patent: 5066683 (1991-11-01), Dillon et al.
patent: 5157058 (1992-10-01), Dillion et al.
patent: 5656279 (1997-08-01), Dillion
Sperling, Interpenetrating Polymer Networks and Related Materials, Plenum Press, New York, 1981, pp. 1-5.
Quinn, KJ, "Silicone Gel in Scar Treatment", Burns, 1987, 13, pp. 33-40.
Dillon, ME, Okunski, WJ, "Silon Non-Adherent Film Dressings on Autograft and Donor Sites", Wounds, 1992, vol. 4, No. 5:203-207.
Perkins, et al., Silocone Gel: A New Treatment for Burn Scars and Contracturers: Burns, 1982, 9, p. 201.
Dillon, ME, "Silicone and Poly(tetrafluoroethylen) Interpenetraiting Polymer Newtorks. Brief History, Summary of Recent . . . " Interpenetraiting Polymer Networks Klempner et al. Ed. ACS Books, New York, NY 1991, pp. 393-404.

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