Semi-continuous fermentation process for aromatic hydrocarbon bi

Details Semi-continuous fermentation process for aromatic hydrocarbon bi Semi-continuous fermentation process for aromatic hydrocarbon bi

1984-06-22

1989-05-23

Tarcza, J. E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

435813, 4352533, 435877, 435311, C12P 744, C12R 140, C12N 120, C12M 112

Patent

active

048330787

ABSTRACT:
This invention provides a semi-continuous fermentation process which is operated in a repeated fed-batch mode to maintain cell bioconversion productivity at a high level without product inhibition of enzymatic activity. The process is illustrated by the bioconversion of toluene or catechol via the ortho pathway to muconic acid which accumulates in the fermentation medium in a quantity up to about 50 grams per liter.

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patent: 4480034 (1984-10-01), Hsieh
patent: 4535059 (1985-08-01), Hsieh et al.

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