Semi-continuous blood separation using magnetic beads

Details Semi-continuous blood separation using magnetic beads Semi-continuous blood separation using magnetic beads

2007-05-08

2007-05-08

Lam, Ann Y. (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

C436S177000

Reexamination Certificate

active

09977930

ABSTRACT:
A container having a flexible wall receives a continuous flow of a biological fluid that includes a target antigen and emits a continuous flow of the biological fluid at least partially depleted from the target antigen. The container further comprises a compartment with magnetic beads coupled to an affinity marker that binds the target antigen, and the target antigen is separated from the biological fluid using a magnetic force and an automatic mechanical force, wherein at least one of the magnetic force and automatic mechanical force is transmitted through the flexible wall.

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patent: 6291249 (2001-09-01), Mahant et al.
patent: 6440725 (2002-08-01), Pourahmadi et al.

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