Semaphorin gene: Semaphorin W

Details Semaphorin gene: Semaphorin W Semaphorin gene: Semaphorin W

2005-06-07

2005-06-07

Chen, Shin-Lin (Department: 1632)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

C435S320100, C435S455000, C536S023100, C536S023500

Reexamination Certificate

active

06902730

ABSTRACT:
The present invention provides Semaphorin W inhibiting neurite outgrowth, and a gene therefor, as well as other Semaphorins hybridizing to said Semaphorin W gene, modified proteins or partial peptides of said Semaphorin W, antibodies against said Semaphorin W, antisense nucleotides against said Semaphorin W gene, and the use of such substances as pharmaceutical or diagnostic agents or laboratory reagents. The present invention further provides a method of screening for Semaphorin W antagonists employing said Semaphorin W, Semaphorin W antagonists obtained by said screening method, pharmaceutical agents comprising such antagonists, and transgenic animals involving said Semaphorin W.

REFERENCES:
patent: 5416197 (1995-05-01), Raper et al.
patent: 5639856 (1997-06-01), Goodman et al.
patent: 5684133 (1997-11-01), Schwab et al.
patent: 5807826 (1998-09-01), Goodman et al.
patent: 5807862 (1998-09-01), Klein et al.
patent: 5935865 (1999-08-01), Goodman et al.
patent: 0396719 (1990-11-01), None
patent: WO 9417831 (1994-08-01), None
patent: WO 9507706 (1995-03-01), None
patent: WO 97/17368 (1997-05-01), None
Skolnick et.al.; From genes to protein structure and function: novel applications of computational approaches in the genomic era, 2000, TIBECH, vol. 18: 34-39.
Kaye et al., A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding, Sep. 1990, Pro. Natl. Sci., vol. 87, pp. 6922-6926.
Hillier et al., EST Accession No. R54387, May 1995.
Bentley et al., a_geneseq36 Accession No. R71384, May 1995.
Igarashi et al., N_Geneseq_0401, Accession No. Q56609, 1994.
Hiller et al., EST Accession No. H24181, 1995.
Kennel, D., 1971, Progr. Nucl. Acid Res. Mol. Biol., vol. 11, p. 259-301.
Matthes et al., Cell, vol. 81, 631-639 (1995).
Messersmith et al., Neuron, vol. 14, 949-959 (1995).
Clifford J. Woolf, Nature, vol. 378, 439-440 (1995).
Eckhardt et al., Molecular and Cellular Neuroscience 9, 409-419 (1997).
Koppel, Neuron, vol. 19, 531-537 (1997).
Furuyama et al., The Journal of Biological Chemistry, vol. 271, No. 52, 33376-33381 (1996).
Mangasser-Stephan et al., Biochemical and Biphysical Research Communications 234, 153-156 (1997).
Herold et al., The Journal of Immunology, “CD100 Is Associated with CD 45 at the Surface of Human T Lymphocytes,” 5262-5268 (1996).
Zhou et al., Molecular and Cellular Neuroscience 9, 26-41 (1997).
Schwab et al, Annu. Rev. Neurosci 16, 565-595 (1993).
Richardson et al., Nature, vol. 284, 264-265 (1980).
David et al., Science, vol. 214, 931-933 (1981).
Schnell et al., Nature, vol. 343, 269-272 (1990).
Luo et al., Cell, vol. 75, 217-227 (1993).
Bregman et al., Nature, vol. 378, 498-501 (1995).
Dodd et al, Cell, vol. 81, 471-474 (1995).
Kolodkin et al., Neuron, vol. 9, 831-845 (1992).
Puschel et al., Neuron, vol. 14, 941-948 (1995).
Kolodkin et al., Cell, vol. 75, 1389-1399 (1993).
Schwab et al., The Journal of Neuroscience 8(7), 2381-2393 (1988).
Bandtlow et al., Science, vol. 259, 80-83 (1993).
Luo et al., Neuron, vol. 14, 1131-1140 (1995).
Alan R. Johnson, BioEssays, vol. 15, No. 12, 807-813 (1993).
Hillier et al., Database Accession No. H10623, Jul. 2, 1995, XP-002214826.
Auffray et al., Database Accession No. Z45329, Nov. 6, 1994, XP-002214827.
Auffray et al., Database Accession No. Z42773, Nov. 6, 1994, XP-002214828.
Caroni et al.,The Journal of Cell Biology, vol. 106, No. 4, Apr. 1, 1988, XP-000600980.
M.D. Adams et al, Nature Genetics 4(4) (1993) pp. 373-380.
Ashwani Khanna et al.; Biochemical and Biophysical Research Communications; vol. 204; No. 3; Nov. 15, 1994; pp. 1061-1066.

Affiliated with

Also associated with

Rating

Semaphorin gene: Semaphorin W does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Semaphorin gene: Semaphorin W, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Semaphorin gene: Semaphorin W will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3469947