Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1997-04-08
1998-09-15
Russel, Jeffrey E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 14, 514 15, 514 16, 514 17, 514 21, A61K 3804, A61K 3816
Patent
active
058078266
ABSTRACT:
A novel class of proteins, semaphorins, nucleic acids encoding semaphorins, semaphorin peptides, and methods of using semaphorins and semaphorin-encoding nucleic acids are disclosed. Semaphorin peptides and receptor agonists and antagonists provide potent modulators of nerve cell growth and regeneration. The invention provides pharmaceutical compositions, methods for screening chemical libraries for regulators of cell growth/differentiation; semaphorin gene-derived nucleic acids for use in genetic mapping, as probes for related genes, and as diagnostic reagents for genetic neurological disease; specific cellular and animal systems for the development of neurological disease therapy.
REFERENCES:
patent: 5639856 (1997-06-01), Goodman et al.
Bentley David R.
Goodman Corey S.
Kolodkin Alex L.
Matthes David
O'Connor Timothy
Osman Richard Aron
Russel Jeffrey E.
The Regents of the University of California
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