Self-setting calcium phosphate cements and methods for preparing

Compositions: coating or plastic – Coating or plastic compositions – Dental

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

106690, 106691, 106792, 623 16, 4332011, C09K 300

Patent

active

059762349

ABSTRACT:
The invention includes methods and compositions relating to calcium phosphate cements, which self-harden substantially to hydroxyapatite at ambient temperature when in contact with an aqueous medium. More specifically the cements comprise a combination of one or more sparingly soluble calcium phosphates other than tetracalcium phosphate with an aqueous solution adjusted with a base to maintain a pH of about 12.5 or above and having sufficient dissolved phosphate salt to yield a solution mixture with phosphate concentration equal to or greater than about 0.2 mol/L.

REFERENCES:
patent: 33161 (1861-02-01), Brown et al.
patent: 33221 (1861-05-01), Brown et al.
patent: 3679360 (1972-07-01), Rubin et al.
patent: 3787900 (1974-01-01), McGee
patent: 3913229 (1975-10-01), Driskell et al.
patent: 3929971 (1975-12-01), Roy
patent: 4097935 (1978-07-01), Jarcho
patent: 4497075 (1985-02-01), Niwa et al.
patent: 4599085 (1986-07-01), Riess et al.
patent: 4880610 (1989-11-01), Constantz
patent: 5034059 (1991-07-01), Constantz
patent: 5047031 (1991-09-01), Constantz
patent: 5053212 (1991-10-01), Constantz et al.
patent: 5129905 (1992-07-01), Constantz
patent: 5336264 (1994-08-01), Constantz et al.
patent: 5455231 (1995-10-01), Constanz et al.
patent: 5496399 (1996-03-01), Ison et al.
patent: 5525148 (1996-06-01), Chow et al.
Kenney, et al., (1988): The Use of a Pourous Hydroxyapatite Implant in Periodontal Defects, J. Periodontal, pp. 67-72, Feb. 1988.
Zide, et al., (1987): Hydroxapatite Cranioplasty Directly Over Dura, J. Oral Maxillofac. Surg. 45:481-486, 1987.
Waite, et al., (1986): Zygomatic Augmentation with Hydroxyapatite, J. Oral Maxillofac. Surg. 44:349-352, 1986.
Verwoerd, et al., (1987): Pourous Hydroxyapatite-perichondrium Graft in Cricoid Reconstruction, Acta Otolaryngol (Stockh) 1987; 103:496-502.
Grote, (1984): Tympanoplasty with Calcium Phosphate, Arch Otolaryngology 110:197-199, 1984.
Kent, et al., (1983): Alveolar Ridge Augmentation Using Nonresorbable Hydroxyapatite with or without Autogenous Cancellous bone, J. Oral Maxillofac. Suge. 41:629-642, 1983.
Piecuch (1986): Augmentation of the Atrophic Edentulous Ridge with Porous Replamineform Hydroxyapatite (Interpore-200), Dental Clinics of North America 30, 2:291-305, 1986.
Misch (1987): Maxillary Sinus Augmentation for Endosteal Implants: Organized Alternative Treatment Plans, Int. J. Oral Implant 4, 2:49058, (1987).
Chow, L.C., "Calcium Phosphate Materials: reactor Response" Adv. Dent. Res. 2(1): 191-184, Aug. (1988).
Fukase, et al., "Setting Reactions and Compressive Strengths of Calcium Phosphate Cements," J. Dent. Res. 69(12): 1852-1856, Dec. 1990.
Chow, et al., "Self-Setting Calcium Phosphate Cements," Mat. Res. Soc. Symp. Proc. vol. 179,(1991).
Miyazaki, et al., "Chemical Change of Hardened PCA/CPC Cements in Various Storing Solutions," The Journal of the Japanese Soc. for Den. Mats. and Devices, vol. 11, No. 2,(1992).
Fukase, et al., "ThermalConductivity of Calcium Phosphate Cement," IADR Abstract,(1990).
Sugawara, et al., "An In Vitro Study of Dentin Hypersensitivity Using Calcium Phosphate Cement," Jour of Jap Soc. for Dent. Mats & Devices, vol. 8, No. 2(1989).
Constantino, et al., "Hydroxyapatite Cement--Basic Chemistry and Histologic Properties," Arch. of Otolaryngology--Head & Neck Surgery, vol. 117, pp. 379-384 (Apr. 1991).
Friedman, et al., "Hydroxyapatite Cement--Obliteration and Reconstruction of the Cat Frontal Sinus," Arch. of Otolaryngology--Head & Neck Surgery, vol. 117, pp. 385-389 (Apr. 1991).
Mirtchi, et al ., "Calcium Phosphate Cements: Study of the .beta.-tricalcium Phosphate-Monocalcium Phosphate system," Biomaterials, vol. 10, pp. 475-480 (1989).
Mirtchi, et al., "Calcium Phosphate Cements: Action of Setting Regulars on the Properties of the .beta.-tricalcium Phosphate-Monocalcium Phosphate System," Biomaterials, vol. 10, pp. 634-638 (1989).
Mirtchi, et al., "Calcium Phosphate Cements: Study of the .beta.-tricalcium PHosphate-Dicalcium Phosphate-Calcite Cements," Biomaterials, vol. 11, pp. 83-88 (1990).
Mirtchi, et al., "Calcium Phosphate Cements: Effect of Fluorides on the Setting and Hardening of the .beta.-tricalcium Phosphate-Dicalcium Phosphate-Calcite Cements," Biomaterials, vol. 12, pp. 505-510 (1991).
Fulmer, et al., "Effects of Na.sub.2 HPO.sub.4 on Hydroxyapatite Formation," J. Biomed. Mat. Res., vol. 27, pp. 1095-1102 (1993).
Ishkawa, et al., "The Hydrolysis of Anhydrous Dicalcium Phosphate into Hydroxyapatite," J. of Dent. res., vol. 72, No. 2, pp. 474-480 (Feb. 1993).
Sugawara, et al., "In Vitro Evaluation of the sealing Ability of a Calcium Phosphate Cement when Used as a Root Canal Sealer-Filler," J. of Endodontics, vol. 16, No. 4, pp. 162-165 (1990).
Shindo, et al., "Facial Skeletal Augmentation Using Hydroxyapatite Cement," arch. of Otolaryngology--Head & Neck Surgery, vol. 119, pp. 185-190 (Feb. 1993).
Costantino, et al., "Experimental Hydroxyapatite Cement Cranioplasty," Plastic and Reconstructive Surgery, vol. 90 No. 2, pp. 174-185 (Aug. 1992).
N. Sanin, K. Ishikawa, S. Takagi, L.C. Chow and E.D. Eanes, "Effects of Additives on Setting Reaction of Calcium Phosphate Cement," IADR Abstr. #666 J. Dent Res. 71 189 (1992).
Driessens, et al.,(1993,) "New Apatite Calcium Phosphate Bone Cement: Preliminary Results," in Bioceramics (Ducheyne & Christiansen, eds.) Butterworth-Heinemann Ltd., vol., 6, pp. 469-473.
Miyazaki, et al., 1993, "Polymeric calcium phosphate cements: analysis of reaction products and properites," Dent. Mater.9:41-45.
Miyazaki et al., 1993, "Polymeric calcium phosphate cements: setting reaction modifiers," Dent. Mater. 9:46-50.
Chow et al., 1994, "Formulation of Hydroxyapatite in Cement Systems," in Hydroxyapatite and Related Materials (Brown & Constanz, eds.), CRC Press: Boca Raton, FL pp. 127-13763.
Constanz, et al., 1995, "Skeletal Repair by Situ Formation of the Mineral Phase of Bone," Science 267: 1796-1798.
Chow and Takagi, 1995, "Rate of Dissolution of Calcium Phosphate Cements," J. Dent,. Res. 74:537 (IADR Abstract #1094).
Takagi and Chow, 1995, "Formation of Macropores in Calcium Phosphate Cement Implants," J. Dent. REs. 74:537 (IADR Abstract #1272).
Horioglu, et al., 1995, "Composite Implant of Hydroxyapatite Cement/Osteogenic Protein-1 in Expermiental Cranial Construction: Preliminary Results," Transactions of the 21st Annual Meeting for the Society of Biomaterials, San Francisco, CA., Mar. 18-22, p. 72.
Driessens, et al., 1995, "Effective formulations for the preparation of calcium phosphate bone cements," J.Mater.Sci.:Mater.Med. 5:164-170.
Fernandez, et al.,(1994), "Common Ion Effect on soem Calcium Phosphate Cements," Clinial Mater.16:99-103).
Matsuya, et al.,(1994), Formation of Hydroxyapatite in a Polymeric Calcium Phosphate Cement, Proc. Int. Conf. Comp. Eng.
Bermudez, et al., Optimization of Calcium Orthophosphat Cement formulation occuring in the combination of monocalcium phosphate monohydrate with calcium oxide, J. Mater.SciMater Med 5:67-71 (No date available).
Dickens-Venz, et al.,(1994) "Physical and chemicali properites of resin-reinforced calcium phosphate cements," Dent.Mater.10:100-106.
Briner, et al., "Significance of Enamel Remineralization," J. Dent. Res. 53:239-243 (1974).
Silverstone, "Remineralization Phenomena," Caries Res, 11 (Supp. 1): 59-84 (1977).
Brown, Solubilities of Phosphates and Other Sparingly Soluble Compounds, from Griffith, et al., Environmental Phosphorous Handbook (John Wiley & Sons, New York (1973).
Miyazaki, et al., "An Infrared Spectroscopic Study of Cement Formation of Polymeric Calcium Phosphate Cement," Journal of Japanese Society for Dental Materials and Devices, vol. II, No. 2, (1992).
Brown and Epstein, "Crystallography of Tetracalcium Phosphate," J. Res. Nat. Bur. Stands, 69A: 547-551 (1965).
Brown and Chow, "Singular Points in the Chemistry of Teeth," IADR Abstract No. 120, J. Dent. Res. 54: 74 (1975).
Driskell, et al., "Development of Ceramic and Ceramic Composite Devices for Maxillofacial Application," J. biomed. Mat. Res. 6: 345-361 (1972).
Gelhard et al., "Rehardening of Artividial Enamel Lesions in Vi

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Self-setting calcium phosphate cements and methods for preparing does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Self-setting calcium phosphate cements and methods for preparing, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Self-setting calcium phosphate cements and methods for preparing will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2129217

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.