Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2007-08-21
2007-08-21
Schnizer, Richard (Department: 1635)
Chemistry: molecular biology and microbiology
Vector, per se
C536S023200, C536S023500, C536S024100
Reexamination Certificate
active
10384136
ABSTRACT:
Disclosed are replicatable viral DNA vectors encoding a site-specific DNA-altering enzyme and a DNA target recognized by the enzyme, the enzyme selectively converting, in a cell expressing the enzyme, the DNA vector to a rearranged form. The invention further relates to methods for assembling recombinant adenoviral DNAs. These methods include the steps of: (a) providing a first linearized DNA vector including a restriction site and a cos site and a second linearized DNA vector including the restriction site, an adenoviral nucleic acid molecule, and a cos site; and (b) ligating the first and second linearized DNA vectors, the ligation assembling a recombinant adenoviral DNA.
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Freeman Mason Wright
Kovtun Alexander
Murakawa Masahiro
Park Eun-Chung
Seed Brian
Clark & Elbing LLP
Schnizer Richard
The General Hospital Corporation
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