Self-gelling liquid composition for topical application in the o

Details Self-gelling liquid composition for topical application in the o Self-gelling liquid composition for topical application in the o

1982-05-24

1983-10-25

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

424 52, A61K 718, A61K 3316

Patent

active

044118899

ABSTRACT:
A self-gelling composition for topical application, particularly in the oral cavity, which composition comprises: an aqueous solution of ethyl orthosilicate monomer or prepolymer; an active ingredient, such as a fluoride, or an antibiotic for sustained release in the area of topical application; and a gelation agent, to provide, on mixing of the composition, the in situ gelling of the composition within a predetermined time period after topical application, to provide the penetration properties of a low-viscosity solution with the sustained release of the active ingredient from the gel.

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