Self-gelling liquid composition for topical application in the o

Details Self-gelling liquid composition for topical application in the o Self-gelling liquid composition for topical application in the o

1983-08-01

1984-06-12

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Ammonia, amine, or derivative thereof

424 49, 424 52, 424181, A61K 716, A61K 718, A61K 722, A61K 3171

Patent

active

044541104

ABSTRACT:
A self-gelling composition for topical application, particularly in the oral cavity, which composition comprises: an aqueous solution of ethyl orthosilicate monomer or prepolymer; an active ingredient, such as a fluoride, or an antibiotic for sustained release in the area of topical application; and a gelation agent, to provide, on mixing of the composition, the in situ gelling of the composition within a predetermined time period after topical application, to provide the penetration properties of a low-viscosity solution with the sustained release of the active ingredient from the gel.

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