Self-emulsifying formulations of cholesteryl ester transfer...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S312000, C514S314000, C514S455000, C514S452000, C514S451000

Reexamination Certificate

active

06962931

ABSTRACT:
CETP Inhibitors have improved solubility and bioavailability in a lipophilic vehicle comprising a digestible oil, a lipophilic solvent, or a surfactant. Preferred such compositions are self-emulsifying or self-microemulsifying, and comprise1. a CETP inhibitor;2. a cosolvent;3. a surfactant having an HLB of 1 to 8;4. a surfactant having an HLB of over 8 to 20; and5. optionally, a digestible oil.

REFERENCES:
patent: 4388307 (1983-06-01), Cavanak
patent: 5958876 (1999-09-01), Woo
patent: 5965160 (1999-10-01), Benita et al.
patent: 5993858 (1999-11-01), Brison et al.
patent: 6140343 (2000-10-01), DeNinno et al.
patent: 6147089 (2000-11-01), DeNinno et al.
patent: 6147090 (2000-11-01), DeNinno et al.
patent: 6197786 (2001-03-01), DeNinno et al.
patent: 6291477 (2001-09-01), Schmidt et al.
patent: 19741399 (1999-03-01), None
patent: 0992496 (2000-04-01), None
patent: 1020439 (2000-07-01), None
patent: WO9320833 (1993-10-01), None
patent: WO9531979 (1995-11-01), None
patent: WO9740823 (1997-11-01), None
patent: WO9748410 (1997-12-01), None
patent: WO9900002 (1999-01-01), None
patent: WO 99/14204 (1999-03-01), None
patent: WO0017164 (2000-03-01), None
patent: WO0017166 (2000-03-01), None
patent: EP 987251 (2000-03-01), None
patent: WO0018723 (2000-04-01), None
patent: WO0040219 (2000-07-01), None
patent: WO0140190 (2001-06-01), None
Hardman et al. “Goodman & Gilman's The Pharmacological Basis of Therapeutics” (9th ed, 1996) p. 51 and 57-58.
Merck Index, 13thEdition, No. 9664, Merck & Co., (2001).
WHO Drug Information, vol. 16, No. 2, 2002, Proposed INN: List 87, pp. 157-193.
*English language equivalent to DE 19741399.
Gordon, et al, “High-density Lipoprotein cholesterol and Cardiovascular Disease”, Circulation, 1989, 79, pp. 8-15.
S. Charman, et al., Pharm Res. vol. 9, 87, 1992.
C. W. Pouton, Adv. Drug Deliv. Rev., vol. 25, pp. 47-58, 1997.
P. P. Constantinides, Pharm. Res., vol. 12, 1561, 1995.
A. Humberstone et al., Adv. Drug Del. Rev., vol. 25, 103, 1997.
Ritschel, Clin. Transplant, vol. 10, pp. 364-373, 1996.
Mueller, Pharm. Res. vol. 11, No. 1, pp. 151-155, 1994.
Shah et al., Intl Jrnl of Pharmaceutics, 108, 1994, pp. 15-23.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Self-emulsifying formulations of cholesteryl ester transfer... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Self-emulsifying formulations of cholesteryl ester transfer..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Self-emulsifying formulations of cholesteryl ester transfer... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3475022

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.