Self-emulsifying and/or emollient agents

Details Self-emulsifying and/or emollient agents Self-emulsifying and/or emollient agents

1994-08-17

1996-11-26

Lovering, Richard D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

252312, 424 59, 424 7022, 514873, 510434, A61K 31225, A61K 742, C11D 320, B01J 1300

Patent

active

055786421

ABSTRACT:
There is provided a composition and process for preparing self-emulsifying or emollient agents comprising reacting from about 1 mole of azelaic acid with from about 1 to about 1.25 moles of a C12-18 fatty alcohol to form an azelaic acid monoester having the general formula I-IV: ##STR1## wherein R is a C12-18 fatty alcohol, and the product contains from about 40 to about 50 weight percent of (I), from about 50 to about 60 weight percent of (II), from about 1 to about 2 weight percent of (III), and from about 0 to about 1 weight percent of (IV), all weights being based on the weight of said self-emulsifying or emollient agent.

REFERENCES:
patent: 2528378 (1950-10-01), Mannheimer
patent: 2781354 (1957-02-01), Mannheimer
patent: 3692822 (1972-09-01), Hay et al.
patent: 3943234 (1976-03-01), Roggenkamp
patent: 3964500 (1976-06-01), Drakoff
patent: 4425458 (1984-01-01), Linder et al.
patent: 4940574 (1990-07-01), Kaplan
patent: 5286397 (1994-02-01), Schmid et al.
patent: 5434237 (1995-07-01), Weinelt et al.
Derwent Abstract, AN-91-074449/11 (Mar. 1991).
Derwent Abstract, AN-80-24318C/14 (Apr. 1980).

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