Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Patent
1982-08-30
1988-06-28
Rosenbaum, C. Fred
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
604 51, A61K 900
Patent
active
047536519
ABSTRACT:
A self-driven pump that delivers a flowable composition at a constant baseline rate and may be manipulated to supplement the baseline rate with one or more pulses of the composition. One pump embodiment consists of a rigid hollow housing with one fixed end wall and one axially moveable end wall; an axially slideable water imbibing assembly mounted transversely in the housing lumen that divides the lumen into a first compartment containing the composition to be dispersed and a second liquid to be imbibed, preferably water, containing compartment. An outlet port extends through the wall of the housing into the first compartment. In operation the subassembly imbibes water from the second compartment and expands into the first compartment to displace the composition therefrom through the outlet at the baseline rate. Pulses are effected by depressing the axially moveable end wall which in turn slides the subassembly toward the fixed end wall thereby exerting pressure on the composition to be dispersed and increasing the injection rate.
REFERENCES:
patent: 4340048 (1982-07-01), Eckenhoff
ALZA Corporation
Macey H.
Mandell Edward L.
Rosenbaum C. Fred
Sabatine Paul L.
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