Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample
Reexamination Certificate
2006-06-13
2006-06-13
Le, Long V. (Department: 1641)
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
Means for analyzing liquid or solid sample
C422S050000, C422S068100, C436S518000, C436S528000, C436S532000, C436S164000, C436S165000, C436S180000
Reexamination Certificate
active
07060225
ABSTRACT:
The invention relates to self-contained assay cassette for detecting a ligand in a sample. The assay cassette provides for turbulent flow and mixing of the sample with assay components, including receptors that bind to a ligand, optional microspheres capable of binding the receptors or to which other secondary receptors are attached, and liquid crystalline materials. The assay cassette also provides for laminar flow of the mixed sample into a detection chamber where complexes between a receptor, ligand, and optional microspheres, is detected as transmission of polarized light through the detection chambers. The invention also relates to methods for detecting a ligand in a sample using turbulent flow to mix the sample with assay components, including liquid crystalline materials, and laminar flow of the mixed sample such that the liquid crystalline material assumes an ordered conformation in absence of a ligand.
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Calfee Halter and Griswold LLP
Le Long V.
Northeastern Ohio Universities College of Medicine
Yu Melanie J
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