Self-calibration of mass spectra using robust statistical...

Details Self-calibration of mass spectra using robust statistical... Self-calibration of mass spectra using robust statistical...

2011-07-12

2011-07-12

DeJong, Eric S (Department: 1631)

Data processing: structural design, modeling, simulation, and em

Simulating nonelectrical device or system

Biological or biochemical

C702S019000, C702S022000, C702S027000

Reexamination Certificate

active

07979258

ABSTRACT:
The use of a robust statistical method for self-calibration of a measuring instrument, such as a mass spectrometer, is disclosed. The method involves the use of differences in mass and complementary pairs for example, to estimate calibration parameters. Self-calibration of various mass spectra is described. Related systems and computer-readable media are also described.

REFERENCES:
patent: 6365893 (2002-04-01), Le Cocq
patent: 6590204 (2003-07-01), Baranov
Aebersold et al. “Mass Spectromtery-based Proteomics” Nature (Mar. 2003) vol. 422, pp. 198-207.
Horn et al. “Automated Reduction and Interpretation of High Resolution Electrospray Mass Spectra of Large Molecules” J. Am. Soc. Mass Spectrom (2000) vol. 11, pp. 320-332.
Anderson et al., “Proteomic characterization of the human centrosome . . . ,” Nature, 426, pp. 570-574 (2003).
Gras et al., “Improving Protein Identification . . . ,” Electrophosesis 20 3535-3550 (1999).
Chernushevich et al., “An Introduction . . . ,” J Mass Spectrom., 2001 (36): 849,865.
Taylor et al., “Implementation . . . ,” Analytical Chemistry, vol. 73, No. 11, (2001), 2594-2604.
Fischler et al., “Random Sample Consensus: A Paradigm for Model Fitting . . . ,” Communication sof the ACM, vol. 24 No. 6, (1981), pp. 381-395.
EP Search Report, EP Application No. 05112476.6-1232/1672673; dated Jun. 30, 2010, Completed May 26, 2010; the Hague.
Christian et al., “Improved Calibration of Time of Flight Mass Spectra by Simplex Optimization of Electrostatic Ion Calculations”, Analytical Chemistry, American Chemical Society, US, vol. 72, No. 14, pp. 3327-3337; Jul. 15, 2000.
Press et al., “Chapter 15: Modeling of Data”, Numerical Recipes in C: The Art of Scientific Computing, 1992, Cambridge University Press, Cambridge, UK, pp. 656-706.
Pop et al., “A New Fuzzy Regression Algorithm”, Analytical Chemistry, vol. 68, No. 5, Mar. 1, 1996, pp. 771-778, Washington, D.C. US.

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