Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Reexamination Certificate
2008-04-22
2008-04-22
Campell, Bruce (Department: 1648)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
C424S202100, C424S192100, C424S184100
Reexamination Certificate
active
07361356
ABSTRACT:
Recombinant papillomavirus capsid proteins that are capable of self assembly into capsomer structures and viral capsids that comprise conformational antigenic epitopes are provided. The capsomer structures and viral capsids, consisting of the capsid proteins that are expression products of a bovine, monkey or human papillomavirus L1 conformational coding sequence proteins, can be prepared as vaccines to induce a high titer neutralizing antibody response in vertebrate animals. The self assembling capsid proteins can also be used as elements of diagnostic immunoassay procedures for papillomavirus infection.
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Kirnbauer Reinhard
Lowy Douglas R.
Schiller John T.
Blumel Benjamin P.
Campell Bruce
Deutsches Krebsforschungszentrum, The German Cancer Research Cen
Knobbe Martens Olson & Bear LLP
The United States of America as represented by the Department of
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