Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1995-06-07
1998-05-26
Knode, Marian C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 5, 435 693, 4352351, 4352402, 4241991, 4241861, 4241301, 4242041, 530350, C12Q 170, C12N 700, A61K 3912, C07K 100
Patent
active
057562849
ABSTRACT:
Recombinant papillomavirus capsid proteins that are capable of self-assembly into capsomer structures and viral capsids that comprise conformational antigenic epitopes are provided. The capsomer structures and viral capsids, consisting of the capsid proteins that are expression products of a bovine, monkey or human papillomavirus L1 conformational coding sequence proteins, can be prepared as vaccines to induce a high-titer neutralizing antibody response in vertebrate animals. The self assembling capsid proteins can also be used as elements of diagnostic immunoassay procedures for papillomavirus infection.
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Kirnbauer Reinhard
Lowy Douglas R.
Schiller John T.
Knode Marian C.
Salimi Ali R.
The United States of America as represented by the Department of
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