Self-assembling polynucleotide delivery system comprising dendri

Details Self-assembling polynucleotide delivery system comprising dendri Self-assembling polynucleotide delivery system comprising dendri

1995-06-06

2000-09-05

Brusca, John S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

514 44, 536 231, A61K 914, A61K 3170, C07H 2100, C07H 2104

Patent

active

061139467

ABSTRACT:
A self-assembling polynucleotide delivery system comprises a dendrimer polycation aiding in the delivery of the polynucleotide to a desired address, and optionally other agents such as DNA masking agents, cell recognition agents, charge-neutralization agents, membrane-permeabilization agents, and subcellular-localization agents.

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