Self-assembling polynucleotide delivery system comprising dendri

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses

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514 2, 514 9, 514 44, 435375, C12N 500, A61K 4800

Patent

active

056610254

ABSTRACT:
A self-assembling polynucleotide delivery system comprises a dendrimer polycation aiding in the delivery of the polynucleotide to a desired address, and optionally other agents such as DNA masking agents, cell recognition agents, charge-neutralization agents, membrane-permeabilization agents, and subcellular-localization agents.

REFERENCES:
patent: 4713975 (1987-12-01), Tomalia et al.
patent: 5264618 (1993-11-01), Felgner et al.

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