Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Mutation employing a chemical mutagenic agent
Patent
1995-06-07
1999-09-21
Marschel, Ardin H.
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Mutation employing a chemical mutagenic agent
424450, 435440, 435443, 435455, 435458, 435466, 514 44, 536 245, C12N 1509
Patent
active
059553650
ABSTRACT:
This invention provides a self-assembling polynucleotide delivery system comprising components aiding in the delivery of the polynucleotide to the desired address which are associated via noncovalent interactions with the polynucleotide. The components of this system include DNA-masking components, cell recognition components, charge-neutralization and membrane-permeabilization components, and subcellular localization components. Specific compounds useful in this system are also provided.
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Haensler Jean
Szoka, Jr. Francis C.
Koenig Nathan P.
Marschel Ardin H.
Regents of the University of California
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