Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Reexamination Certificate
2011-06-21
2011-06-21
Peng, Bo (Department: 1648)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
C424S194100, C424S196110, C424S201100, C424S202100, C424S227100, C424S192100, C530S350000, C530S402000, C977S795000, C977S797000, C977S798000, C977S800000, C977S801000, C977S802000
Reexamination Certificate
active
07964196
ABSTRACT:
A self-assembling nanoparticle drug delivery system for the delivery of drugs including peptides, proteins, nucleic acids or synthetic chemical drugs is provided. The self-assembling nanoparticle drug delivery system described herein includes viral capsid proteins, such as Hepatitis B Virus core protein, encapsulating the drug, a lipid bi-layer envelope and targeting or facilitating molecules anchored in the lipid bilayer. A method for construction of the self-assembling nanocparticle drug delivery system is also provided.
REFERENCES:
patent: 5133961 (1992-07-01), Ellis et al.
patent: 5420026 (1995-05-01), Payne
patent: 5439686 (1995-08-01), Desai et al.
patent: 5498421 (1996-03-01), Grinstaff et al.
patent: 5620689 (1997-04-01), Allen et al.
patent: 5670630 (1997-09-01), Thill
patent: 5714316 (1998-02-01), Weiner et al.
patent: 5858726 (1999-01-01), Payne
patent: 5863541 (1999-01-01), Samulski et al.
patent: 5980901 (1999-11-01), Shih et al.
patent: 6046173 (2000-04-01), Forstova et al.
patent: 6063370 (2000-05-01), Dadey
patent: 6096331 (2000-08-01), Desai et al.
patent: 6204059 (2001-03-01), Samulski et al.
patent: 6231864 (2001-05-01), Birkett
patent: 6387662 (2002-05-01), Liang et al.
patent: 6420160 (2002-07-01), Bloch
patent: 6506405 (2003-01-01), Desai et al.
patent: 6506559 (2003-01-01), Fire et al.
patent: 6537579 (2003-03-01), Desai et al.
patent: 6573009 (2003-06-01), Noda et al.
patent: 6602706 (2003-08-01), Fallaux et al.
patent: 6602932 (2003-08-01), Feldheim et al.
patent: 6616944 (2003-09-01), Kissel et al.
patent: 6620617 (2003-09-01), Mathiowitz et al.
patent: 6627202 (2003-09-01), Murray
patent: 6696038 (2004-02-01), Mahato et al.
patent: 6710173 (2004-03-01), Binley et al.
patent: 6749868 (2004-06-01), Desai et al.
patent: 6753006 (2004-06-01), Desai et al.
patent: 6984386 (2006-01-01), Douglas et al.
patent: 7056704 (2006-06-01), Tuschl et al.
patent: 7078194 (2006-07-01), Withers et al.
patent: 7101995 (2006-09-01), Lewis et al.
patent: 7282199 (2007-10-01), Gao et al.
patent: 7332321 (2008-02-01), Belcher et al.
patent: 7332337 (2008-02-01), van Es et al.
patent: 7344872 (2008-03-01), Gao et al.
patent: 7422902 (2008-09-01), Wheeler et al.
patent: 2004/0005338 (2004-01-01), Bachmann et al.
patent: 2004/0247660 (2004-12-01), Singh
patent: 2005/0004002 (2005-01-01), Desai et al.
patent: 2005/0089526 (2005-04-01), Moore et al.
patent: 2006/0292118 (2006-12-01), Kuroda et al.
patent: 2006/0292174 (2006-12-01), de los Rios et al.
patent: 2007/0248573 (2007-10-01), Sturino
patent: 2007/0249554 (2007-10-01), Tuszynski
patent: 2007/0258889 (2007-11-01), Douglas et al.
patent: 2007/0269370 (2007-11-01), Davis et al.
patent: 2007/0280962 (2007-12-01), Murray
patent: 2008/0050343 (2008-02-01), Wilson et al.
patent: 2008/0050345 (2008-02-01), Wilson et al.
patent: 2008/0069802 (2008-03-01), Davis et al.
patent: 2008/0075737 (2008-03-01), Gao et al.
patent: 2008/0075740 (2008-03-01), Gao et al.
patent: 2008/0090281 (2008-04-01), Wilson et al.
patent: 2008/0125385 (2008-05-01), Hajjar et al.
patent: 2008/0131928 (2008-06-01), Handa et al.
patent: 2009/0226525 (2009-09-01), de los Rios et al.
patent: 0863987 (1998-09-01), None
patent: 0920514 (1999-06-01), None
patent: 1204761 (2002-05-01), None
patent: 1219705 (2002-07-01), None
patent: 1447079 (2004-08-01), None
patent: 1563834 (2005-08-01), None
patent: 1845163 (2007-10-01), None
patent: 1849799 (2007-10-01), None
patent: 1944043 (2008-07-01), None
patent: WO-95/32706 (1995-12-01), None
patent: WO 99/40214 (1999-02-01), None
patent: 9940214 (1999-08-01), None
patent: 0009158 (2000-02-01), None
patent: 0102551 (2001-01-01), None
patent: WO-01/12235 (2001-02-01), None
patent: 0244204 (2002-06-01), None
patent: 2004047812 (2004-06-01), None
patent: WO-2006/033679 (2006-03-01), None
patent: WO-2006/066048 (2006-06-01), None
patent: WO-2007/126764 (2007-11-01), None
patent: WO-2007/136263 (2007-11-01), None
patent: WO-2008/008881 (2008-01-01), None
patent: WO-2008/010864 (2008-01-01), None
patent: WO-2008/021908 (2008-02-01), None
patent: WO-2008/024427 (2008-02-01), None
patent: WO-2008/027084 (2008-03-01), None
patent: WO-2008/037504 (2008-04-01), None
patent: WO-2008/048288 (2008-04-01), None
patent: WO-2008/051101 (2008-05-01), None
patent: WO-2008/054826 (2008-05-01), None
patent: WO-2008/124165 (2008-10-01), None
Jenny R et al. “Acritical review of the methods for cleavage of fusion proteins with thrombin and factor Xa” Protein Expression and Purification 31(2-3):1-11, 2003, cited in IDS).
Lundstrom K et al. “Breakthrough in cancer therapy:encapsulation of drugs and viruses” Curr. Drug Disc (2002) Nov. 19-23, Cited in IDS.
Moghimi SM et al. “Long-circulating and target-specific nanoparticles: theory to practice” Pharmarceutical Review, 53(2):283-318, 2001, cited in IDS.
Moreira J. et al. “Use of the post-insertion technique to insert peptide ligands into pre-formed Stealth liposomes with retention of binding activity and cytotoxicity” Pharmaceutical Research 19(3):265-269, 2002.
Scott MD, et al. “Chemical camouflage of antigenic determinants: stealth erythrocytes” Proc Natl Acad Sci U S A. Jul. 8, 1997;94(14):7566-71.
Yamada, T. et al., “Nanoparticles for the Delivery of Genes and Drugs to Human Hepatocytes”, Nature Biotechnology, vol. 21, No. 8, 2003, pp. 885-890.
Boisgerault F et al. “Virus-like particles: a new family of delivery systems.” Expert Rev. Vaccines 1(1):101-9, 2002.
Brunfield S et al. “Heterologous expression of the modified coat protein of Cowpea chlorotic mottle bromovirus results in the assembly of protein cages with altered architecture and function.” J Gen Virol 85:1049-1053, 2004.
Crommelin Dja et al. “Nanotechnological approaches for the delivery of macromolecules.” J Controlled Release 87:81-88, 2003.
Haag R. “Supramolecular drug-delivery systems based on polymeric core-shell architectures.” Angew Chem Int Ed 43:278-282, 2004.
Jenny RJ et al. “A critical review of the methods for cleavage of fusion proteins with thrombin and factor Xa.” Prot Express Purif 31:1-11, 2003.
Kayser O et al. “Formulation and biopharmaceutical issues in the development of drug delivery systems for antiparasitic drugs.” Parasitol Res 90:S63-S70, 2003.
Liu J et al. “Nanostructured materials designed for cell binding and transduction.” Biomacromolecules 2:362-368, 2001.
Lundstrom K et al. “Breakthrough in cancer therapy: encapsulation of drugs and viruses.” Curr Drug Disc : Nov. 2002, pp. 19-23.
Managit C et al. “Targeted and sustained drug delivery using PEGylated galatosylated liposomes.” Int J Pharmaceutics 266:77-84, 2003.
Moghimi SM et al. “Long-circulating and target-specific nanoparticles: theory to practice.” Pharmacol Rev 53:283-318, 2001.
Sahoo SK et al. “Nanotech approaches to drug delivery and imaging.” Drug Disc Today 8:1112-1120, 2003.
Schmidt U et al. “Protein and peptide delivery via engineered polyomavirus-like particles.” FASEB J 15:1646-1648, 2001.
Schmidt U et al. “Binding of external ligands onto an engineered virus capsid.” Protein Eng 14:769-774, 2001.
Sinha VR et al. “Biodegradable microspheres for protein delivery.” J Controlled Rel 90:261-280, 2003.
Rocco MC et al. “Social Implications of Nanoscience and Technology.” National Science Foundation Report, 2001.
Panyam J et al. “Biodegradable nanoparticles for drug and gene delivery to cells and tissue.” Adv Drug Del Rev 55:329-47, 2003.
Lamprecht et al. “Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease.” J Pharmacol Exp Ther 299:775-81, 2002.
Monsky WL et al. “Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor.” Cancer Res. 59:4129-35, 1999.
Panyam J et al. “Fluorescence and electron
de los Rios Miguel
Oh Kenneth J.
Chimeros, Inc.
Goodwin & Procter LLP
Peng Bo
LandOfFree
Self-assembling nanoparticle drug delivery system does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Self-assembling nanoparticle drug delivery system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Self-assembling nanoparticle drug delivery system will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2725639