Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 15 to 23 amino acid residues in defined sequence
Patent
1996-08-23
2000-08-01
Celsa, Bennett
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
15 to 23 amino acid residues in defined sequence
424417, 424450, 554 1, 560 1, 530300, C07K 700, A61K 9127, C07C 5500, C07C 6900
Patent
active
06096863&
ABSTRACT:
A peptide-amphiphile complex having a lipophilic portion and a peptide portion, wherein the peptide portion has a secondary structure.
REFERENCES:
patent: 4732971 (1988-03-01), DiMarchi et al.
patent: 5117009 (1992-05-01), Barany
patent: 5196566 (1993-03-01), Barany et al.
patent: 5366958 (1994-11-01), Weiner et al.
patent: 5401511 (1995-03-01), Margalit
patent: 5498420 (1996-03-01), Edgar et al.
patent: 5576419 (1996-11-01), Fields
Hantke et al, Covalent binding of lipids to protein. Eur. J. Biochem. 34: 284-296, 1973.
McLachlan, A.D., The Double helix coiled coil structure of Murein Lippoprotein from Escherichia Coli. J. Mol. Biol. 122,: 493-506, 1978.
Shimizu T, et al, (1989) Enhanced circular dichoism of self-assembled peptidic amphiphiles. Chem.Lett. 8:1341-1344, 1989.
Yu YC, et al, (Jun. 24, 1995) Study of triple-helical structure using peptide-amphiphiles. 14th American peptide symposia 515-516, 1995.
Yu et al., "Study of triple-helical structure using peptide-amphiphiles," Chemical Abstracts, 126(1), Abstract No. 8687 (1997).
F. Albericio et al., "Preparation and Application of the 5-(4-(9-Flyorenyl methyloxycarbonyl)aminomethyl-3,5-dimethoxyphenoxy)-valeric Acid (PAL) Handle for the Solid-Phase Synthesis of C-Terminal Peptide Amides under Mild Conditions", J. Org. Chem., 55, 3730-3743 (1990).
Barany et al., "Solid-phase synthesis: a silver anniversary report", Int. J. Peptide Protein Res., 30, 705-739 (1987).
Barany et al., "Solid-Phase Peptide Synthesis", The Peptides, vol. 2, Title Page, Copyright, and Table of Contents (pp. v-viii) (1980).
P. Berndt et al., "Synthetic Lipidation of Peptides and Amino Acids: Monolayer Structure and Properties", Amer. Chem. Soc., 117, 9515-9522 (1995).
Casey, "Protein Lipidation in Cell Signaling", Science, 268, 221-225 (1995).
de Bont et al., "A convenient synthesis of a lipopeptide containing a diacylglycerol moiety: preparation of a potential inhibitor of protein kinase C", Recl. Trav. Chim. Pays-Bas, 111, 222-226 (1992).
C.G. Fields et al., "Edman Degradation Sequence Analysis of Resin-Bound Peptides Synthesized by 9-Fluorenylmethoxycarbonyl Chemistry", Peptide Research, 6, 39-47 (1993).
C.G. Fields et al., "HBTU Activation for Automated Fmoc Solid-Phase Peptide Synthesis", Peptide Research, 4, 95-101 (1991).
C.G. Fields et al., "Melanoma Cell Adhesion and Spreading Activities of a Synthetic 124-Residue Triple-helical `Mini-collagen`", J. Biol. Chem., 268, 14153-14160 (1993).
C.G. Fields et al., "Minimization of Tryptophan Alkylation Following 9-Fluorenylmethoxycarbonyl Solid-Phase Peptide Synthesis", Tetrahedron Lett., 34, 6661-6664 (1993).
C.G. Fields et al., "Purification and Analysis of Synthetic, Triple-Helical `Minicollagens` by Reversed-Phase High-Performance Liquid Chromatography", Anal. Biochem.,231, 57-64 (1995).
C.G. Fields et al., "Solid-Phase Synthesis and Stability of Triple-Helical Peptides Incorporating Native Collagen Sequences", Biopolymers, 33, 1695-1707 (1993).
C.G. Fields et al., "Solid-phase synthesis of triple-helical collagen-model peptides", Lett. Peptide Sci., 3, 3-16 (1996).
G.B. Fields, NIH #DK44494 (Abstract Only), Sep. 30, 1992.
G.B. Fields, NIH #AR01929 (Abstract Only), Mar. 1, 1994.
G.B. Fields et al., "Principles and Practice of Solid-Phase Peptide Synthesis", Synthetic Peptides: A User's Guide (G.A. Grant, Ed.), W.H. Freeman and Co., N.Y., Chapter 3, pp. 77-183 (1992).
G.B. Fields et al., "Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids", Int. J. Peptide Protein Res., 35, 161-214 (1990).
G.B. Fields, "The Collagen Triple-Helix: Correlation of Conformation With Biological Activities", Connect. Tissue Res., 31, 235-243 (1995).
Grab et al., "Promotion of Fibroblast Adhesion by Triple-helical Peptide Models of Type I Collagen-derived Sequences", J. Biol. Chem., 271, 12234-12240 (1996).
Jain et al., "Synthesis of Peptidylglycophospholipids, Novel Derivatives of Muramyl-Dipeptide", Tetrahedron Lett., 22, 2317-2320 (1981).
King et al., "A cleavage method which minimizes side reactions following Fmoc solid phase peptide synthesis", Int. J. Peptide Protein Res., 36, 255-266 (1990).
Lauer et al., "Sequence dependence of aspartimide formation during 9-fluorenylmethoxycarbonyl solid-phase peptide synthesis", Lett. Peptide Sci., 1, 197-205 (1994).
Merrifield, "Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide", J. Am. Chem. Soc., 85, 2149-2154 (1963).
Miles et al., "Promotion of Cell Adhesion by Single-stranded and Triple-helical Peptide Models of Basement Membrane Collagen .alpha.1(IV)531-543", J. Biol. Chem., 269, 30939-30945 (1994).
Morton et al., "Platelet Aggregation by a Collagen-Like Synthetic Peptide", Thrombosis Res., 72, 367-372 (1993).
W. Prass et al., "Lipopeptides of the N-terminus of Escherichia coli lipoprotein: synthesis, mitogenicity and properties in monolayer experiments", Biochim. et Biophys. Acta, 900, 116-128 (1987).
Rao et al., "Promotion of Human Platelet Adhesion and Aggregation by a Synthetic, Triple-helical `Mini-collagen`", J. Biol. Chem., 269, 13899-13903 (1994).
M.B. Sankaram, "Membrane Interaction of Small N-Myristoylated Peptides: Implications for Membrane Anchoring and Protein-Protein Association", J. Biophys., 67, 105-112 (1994).
T. Shimizu et al., "Self-assembling properties of synthetic peptidic lipids", Biochem. et Biophys. Acta, 1147, 50-58 (1993).
Thompson et al., "Covalent Linkage of a Synthetic Peptide to a Fluorescent Phospholipid and Its Incorporation Into Supported Phospholipid Monolayers", Biochim. Biophys. Acta., 772, 10-19 (1984).
Y. Yu et al., "Self-Assembling Amphiphiles for Construction of Protein Molecular Architecture", J. Amer. Chem. Soc., 118, 12515-12520 (1996).
Fields Gregg B.
Tirrell Matthew V.
Celsa Bennett
Regents of the University of Minnesota
Ricigliaw Joseph W.
LandOfFree
Self-assembling amphiphiles for construction of peptide secondar does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Self-assembling amphiphiles for construction of peptide secondar, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Self-assembling amphiphiles for construction of peptide secondar will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-665071