Self-assembled metal colloid monolayers and detection methods th

Details Self-assembled metal colloid monolayers and detection methods th Self-assembled metal colloid monolayers and detection methods th

1998-12-16

2000-02-15

Soderquist, Alren

Chemistry: analytical and immunological testing

Phosphorus containing

Organic

436 86, 436103, 436105, 436161, 436171, 436501, 356301, 356318, 422 89, G01N 3300, G01J 344

Patent

active

060252022

ABSTRACT:
A biosensor based on complexes between biomolecule receptors and colloidal Au nanoparticles, and more specifically, colloid layers of receptor/Au complexes that can be used to detect biomolecule analytes through measuring of binding-induced changes in electrical resistance or surface plasmon resonance. Also disclosed is a method for detecting and analysing carrier-borne chemical compounds with Raman spectroscopy using an improved SERS substrate. Further disclosed is an improved method for detecting compounds in solvents using capillary electrophoresis in conjunction with Raman spectroscopy.

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