Self-assembled lipid bilayer materials

Stock material or miscellaneous articles – Web or sheet containing structurally defined element or... – Physical dimension specified

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C428S220000, C428S336000, C424S001210, C424S450000, C436S829000

Reexamination Certificate

active

06962747

ABSTRACT:
The present invention is a self-assembling material comprised of stacks of lipid bilayers formed in a columnar structure, where the assembly process is mediated and regulated by chemical recognition events. The material, through the chemical recognition interactions, has a self-regulating system that corrects the radial size of the assembly creating a uniform diameter throughout most of the structure. The materials form and are stable in aqueous solution. These materials are useful as structural elements for the architecture of materials and components in nanotechnology, efficient light harvesting systems for optical sensing, chemical processing centers, and drug delivery vehicles.

REFERENCES:
patent: 5837202 (1998-11-01), Arnold et al.
patent: 5925375 (1999-07-01), Lenk et al.
patent: 6284267 (2001-09-01), Aneja
patent: 6358523 (2002-03-01), Safinya et al.
patent: 6537575 (2003-03-01), Firestone et al.
Waggoner, et al., “Self-Assembled Columns of Stacked Lipid Bilayers Mediated by Metal Ion Recognition,”J. Am. Chem. Soc., 2001, 123, 496-497 (no month).
Ringsdorf, et al., “Molecular Architecture and Function of Polymeric Oriented Systems: Models for the Study of Organization, Surface Recognition, and Dynamics of Biomembranes”Angew. Chem. Int. Ed. Engl.; 27, 113-158, Jan. 1988.
Alberts, et al., “Molecular Biology of The Cell, 3rd ed.” Garland Publishing, 1994, pp. 127-128, 276, 576, 1142-1143 (no month).
Radler, et al., “Structure of DNA-Cationic Liposome Complexes: DNA Intercalation in Multilameller Membranes in Distinct Interhelical Packing Regimes,”SCIENCE, vol. 275, Feb. 7, 1997, 810-813 (www.sciencemag.org).
Wong, et al., “Hierarchical Self-Assembly of F-Actin and Cationic Lipid Complexes: Stacked Three-Layer Tubule Networks,”SCIENCE, vol. 288, Jun. 16, 2000, 2035-2039 (www.sciencemag.org).
Constable, et al., “Reversible metal-directed assembly of clusters and vesicles”Chem. Commun., 1999, 1483-1484 (no month).
Chiruvolu, et al., “Higher Order Self-Assembly of Vesicles by Site-Specific Binding,”SCIENCE, vol. 264, Jun. 17, 1994, 1753-1756 (www.sciencemag.org).
Sasaki, et al., “Optical detection of aqueous phase analytes via host-guest interaction on a lipid membrane surface,”SPIE-The International Society for Optical Engineering, vol. 3606, Jan. 25-26, 1999, San Jose, CA, 46-54.
Sasaki, et al., “Metal-Induced Dispersion of Lipid Aggregates: A Simple, Selective, and Sensitive Flourescent Metal Ion Sensor,”Angew. Chem. Int. Ed. Engl., 1995, 34, No. 8, 905-907 (no month).
Sasaki and Padilla, “Dithioamide Metal Ion Receptors on Flourescent Lipid Bilayers for the Selective Optical Detection of Mercuric Ion,”Chem. Commun., 1998, 1581-1582 (no month).
Ng, et al., “Engineering Protein-Lipid Interactions: Targeting of Histidine-Tagged Proteins to Metal-Chelating Lipid Monolayers,”Langmuir, vol. 11, No. 10, 1995,Am. Chem. Soc., 4048-4055 (no month).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Self-assembled lipid bilayer materials does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Self-assembled lipid bilayer materials, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Self-assembled lipid bilayer materials will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3472620

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.