Self-assembled, defective, nonself-propagating viral particles

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses

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4242081, 435236, C12N 1500, C12N 704, A61K 3921

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active

060514108

ABSTRACT:
Recombinant viral vectors which coexpress heterologous polypeptides capable of assembling into defective nonself-propagating viral particles are disclosed. The viral vectors as well as the viral particles can be used as immunogens and for targeted delivery of heterologous gene products and drugs.

REFERENCES:
patent: 4603112 (1986-07-01), Paoletti et al.
patent: 5614404 (1997-03-01), Mazzara et al.
S. Hu. et al., Nature. 302:537-540 (1986).
S. Chakrabarti, et al., Nature 320: 535-537 (1986).
M.P. Kieny, et al., Biotechnology, 4:790-795 (1986).
J.M. Zarting, et al., Nature. 323:344-346 (1986).
S. Hu, et al., Nature. 328:721-723 (1987).
D. Zagury. et al., Nature. 326:249-250 (1987).
D. Zagury, et al., Nature. 332:728-731 (1988).
G.L. Smith, et al., Gene, 25:21-28 (1983).
T. Shioda, et al., Virology, 175:139-148 (1990).
D. Panicali, et al., Proc. Natl. Acad. Sci. USA, 79:4927-4931 (1982).
D. Panicali, et al., Proc. Natl. Acad. Sci. USA, 80:5364-5368 (1993).
O. Haffar, et al., J. Virol. 64:2653-2659 (1990).
V. Karacostas et al., Natl. Proc. Natl. Acad. Sci. USA, 86:8964-8967 (Nov. 1989).
M. E. Perkus, et al., Science, 229:981-984 (1985).
M. Delchambre, et al., The EMBO J. 8:2653-2660 (1989).
M.L. Bosch et al., Science, 244:694-697 (1989).
S.D. Gowda et al., J. Biol. Chem., 264:8459-8460 (May 1989).
G. Raumann, et al., AIDS Res. Hum. Retroviruses 5:147-157 (Apr. 1989).
S.D. Gowa, et al., J. Virol. 63:1451-1454 (1989).
S.A. Popov, et al., Mol. Gen. Mikrobiol. Virusol. 9:36-39 (Sep. 1988).
C. Flexner, et al., Virology, 166:339-349 (Oct. 1988).
G. Mazzara, et al., Modern Approaches to Vaccines, Cold Spring Harbor Laboratory, New York (1987).
D. Gheysen, et al., Modern Approaches to New Vaccines, Cold Spring Harbor Laboratory, New York, Sep. 14-18, 1988, Abstract No. 72 International Search Report.
D. Gheysen, et al., Cell 59:103 (1989).
Internationa Preliminary Examination Report.
B.N. Fields, et al., Eds Fundamental Virology, 2nd Ed. New York: Raven Press, 1991, pp. 16.92-93.
R. Mann, et al., (1983) Cell 33:153-159.
A. Lever, et al., (1989) J. Virology 63(9):4085-4087.
International Search Report for the corresponding Patent Cooperation Treaty application.

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