Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1995-06-07
1998-09-08
Achutamurthy, Ponnathapura
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
4351723, 514 44, A61K 3921, C12N 1500, A01N 4304
Patent
active
058041966
ABSTRACT:
Recombinant avipox viral vectors which express heterologous polypeptides capable of assembling into defective nonself-propagating viral particles are disclosed. The recombinant avipox viruses can be used to produce significant amounts of the heterologous polypeptides in avian or non-avian cells. Preferably, the recombinant avipox virus is a fowlpox virus. The viral particles can also be used as immunogens and for targeted delivery of heterologous gene products and drugs.
REFERENCES:
patent: 4603112 (1986-07-01), Paoletti et al.
D.B. Boyle and E.H. Coupar, Virus Research 10:343-356 (1988).
J. Taylor, et al., Vaccine 6:497-503 (1988).
J. Taylor, et al. Vaccine 6:504-508 (1988).
D. B. Boyle and B.E.H. Coupar, J. Gen. Virol., 67:1591-19600 (1986).
D.B. Boyle, et al., Virology, 156:355-365 (1987).
F. Tomley, et al., J. Gen. Virol., 69:1025-1040 (1988).
M.M. Binns, et al., Virology, 170:288-291 (1989).
J. Taylor, et al., Technological Advances in Vaccine Development, (1988), L. Lasky (Ed.), Alan R. Liss, Inc., New York, pp. 321-334.
M.M. Binns, et al., Israeli J. Vet. Med., 42:124-127 (1986).
G. Rautmann, et al., AIDS Res. Hum. Restroviruses, 5:147-157 (1989).
C.D. Gowda, et al., J. Virol. 63:1451-1454 (Mar. 1989).
G. Mazzara, et al., Modern Approaches to Vaccines, Cold Spring Harbor Laboratory, New York, (1987).
G. Gheysen, et al., Modern Approaches to New Vaccines, Cold Spring Harbor Laboratory, New York, Sep. 14-18, Abstract No. 72 (1988).
D. Gheysen, et al., Cell, 59:103 (1989).
Smith, et al., J. Virol., 64:2743-2750 (1990).
J.W. Wills, Nature, 340:323-324 (1989).
T. Shioda and H. Shibuta, Virology, 175:139-148 (1990).
O. Haffar, et al., J. Virol. 64:2653-2659 (Jun. 1990).
V. Karacostas, et al., Proc. NAtl. Acad. Sci. USA 86:8964-8967 (Nov. 1989).
M. Delchambre, et al., The EMBO J. 8:2653-2660 (1989).
M.E. Perkins, et al., (1985) Science 229:981-984.
R. Mann et al., (1989) J. Virol, 63:4085-4087.
A. Lever, et al., (1989), J. Virol, 63:4085-4087.
G. Franchin, et al., (1987) Nature, 328:539-543.
Fahey et al., Status of immune-based therapies in HIV infection and AIDS Clin. Exp. Immunol. (1992) 88, 1-5.
Fox, J.L., No winners against AIDS, Bio/Technology, (1994) vol. 12, Feb. p. 128.
Gritz Linda R.
Mazzara Gail P.
Panicali Dennis L.
Roberts Bryan
Stallard Virginia
Achutamurthy Ponnathapura
Bronstein Sewall P.
Eisenstein Ronald I.
Park Hankyel T.
Resnick David S.
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