Self-assembled, defective, non-self-propagating lentivirus parti

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Inactivation or attenuation; producing viral subunits

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435 691, 435 693, 4351723, 4353201, 930221, C12N 1586, C12N 1563, A61K 3921, C07K 14155

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active

056144040

ABSTRACT:
Recombinant viral vectors which coexpress heterologous polypeptides capable of assembling into defective nonself-propagating viral particles are disclosed. The viral vectors as well as the viral particles can be used as immunogens and for targeted delivery of heterologous gene products and drugs.

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